200006859
MMP2 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MMP2
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01
Gene Symbols
MMP2
Primary or Secondary
Primary
Content And Storage
-20°C
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P08253
Gene ID (Entrez)
4313
Immunogen
E.coli-derived, 62.0 kDa Recombinant Human MMP-2
Purification Method
Affinity chromatography
Gene
MMP2
Description
- AA Seq: MYNFFPRKPK WDKNQITYRI IGYTPDLDPE TVDDAFARAF QVWSDVTPLR FSRIHDGEAD IMINFGRWEH GDGYPFDGKD GLLAHAFAPG TGVGGDSHFD DDELWTLGEG QVVRVKYGNA DGEYCKFPFL FNGKEYNSCT DTGRSDGFLW CSTTYNFEKD GKYGFCPHEA LFTMGGNAEG QPCKFPFRFQ GTSYDSCTTE GRTDGYRWCG TTEDYDRDKK YGFCPETAMS TVGGNSEGAP CVFPFTFLGN KYESCTSAGR SDGKMWCATT ANYDDDRKWG FCPDQGYSLF LVAAHEFGHA MGLEHSQDPG ALMAPIYTYT KNFRLSQDDI KGIQELYGAS PDIDLGTGPT PTLGPVTPEI CKQDIVFDGI AQIRGEIFFF KDRFIWRTVT PRDKPMGPLL VATFWPELPE KIDAVYEAPQ EEKAVFFAGN EYWIYSASTL ERGYPKPLTS LGLPPDVQRV DAAFNWSKNK KTYIFAGDKF WRYNEVKKKM DPGFPKLIAD AWNAIPDNLD AVVDLQGGGH SYFFKGAYYL KLENQSLKSV KFGSIKSDWL GC Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-2
- Anti-Human MMP-2-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human MMP-2 by sandwich ELISA (using 100 μL/well) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human MMP-2 (500-P307) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human MMP-2
- Western Blot: To detect Human MMP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2μg/ml
- When used in conjunction with compatible development reagents the detection limit for Recombinant Human MMP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- MMP (matrix metalloproteinase) are proteolytic enzymes capable of degrading connective tissue components
- MMP have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs)
- MMPa and TIMPs play a significant role in regulating angiogenesis
- MMP2 is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids, and contains the basic structure of propeptide, catalytic, and hemopexin domains
- The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane-bound zincendopeptidases
- Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non-fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins
- In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc-binding site characterizes the structure of the MMPs
- Functionally, MMP2 is involved in tissue remodeling
- Mutations in MMP-2 gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome
- Two transcript variants encoding different isoforms of MMP-2 have been found.
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Antigen: MMP2
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01
Gene Symbols: MMP2
Primary or Secondary: Primary
Content And Storage: -20°C
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P08253
Gene ID (Entrez): 4313
Immunogen: E.coli-derived, 62.0 kDa Recombinant Human MMP-2
Purification Method: Affinity chromatography
Gene: MMP2
Antigen:
MMP2
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01
Gene Symbols:
MMP2
Primary or Secondary:
Primary
Content And Storage:
-20°C
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P08253
Gene ID (Entrez):
4313
Immunogen:
E.coli-derived, 62.0 kDa Recombinant Human MMP-2
Purification Method:
Affinity chromatography
Gene:
MMP2
Antigen: FGF23
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: ADHR, FGF, Fgf23, FGF-23, FGFN, Fibroblast growth factor, Fibroblast growth factor 23, Fibroblast growth factor 23 C-terminal peptide, Fibroblast growth factor 23 N-terminal peptide, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor, UNQ3027/PRO9828
Gene Symbols: FGF23
Primary or Secondary: Primary
Content And Storage: -20°C
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9GZV9
Gene ID (Entrez): 8074
Immunogen: E.coli-derived, 25.5kDa Recombinant Human FGF-2
Purification Method: Affinity chromatography
Gene: FGF23
Antigen:
FGF23
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
ADHR, FGF, Fgf23, FGF-23, FGFN, Fibroblast growth factor, Fibroblast growth factor 23, Fibroblast growth factor 23 C-terminal peptide, Fibroblast growth factor 23 N-terminal peptide, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor, UNQ3027/PRO9828
Gene Symbols:
FGF23
Primary or Secondary:
Primary
Content And Storage:
-20°C
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9GZV9
Gene ID (Entrez):
8074
Immunogen:
E.coli-derived, 25.5kDa Recombinant Human FGF-2
Purification Method:
Affinity chromatography
Gene:
FGF23
Antigen: FGF23
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: ADHR, FGF, Fgf23, FGF-23, FGFN, Fibroblast growth factor, Fibroblast growth factor 23, Fibroblast growth factor 23 C-terminal peptide, Fibroblast growth factor 23 N-terminal peptide, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor, UNQ3027/PRO9828
Gene Symbols: FGF23
Primary or Secondary: Primary
Content And Storage: -20°C
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9GZV9
Gene ID (Entrez): 8074
Immunogen: E.coli-derived, 25.5kDa Recombinant Human FGF-2
Purification Method: Affinity chromatography
Gene: FGF23
Antigen:
FGF23
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
ADHR, FGF, Fgf23, FGF-23, FGFN, Fibroblast growth factor, Fibroblast growth factor 23, Fibroblast growth factor 23 C-terminal peptide, Fibroblast growth factor 23 N-terminal peptide, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor, UNQ3027/PRO9828
Gene Symbols:
FGF23
Primary or Secondary:
Primary
Content And Storage:
-20°C
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9GZV9
Gene ID (Entrez):
8074
Immunogen:
E.coli-derived, 25.5kDa Recombinant Human FGF-2
Purification Method:
Affinity chromatography
Gene:
FGF23
Antigen: CD3
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: 4930549J05Rik, A430104F18Rik, AI504783, antigen CD3D, delta polypeptide (TiT3 complex), antigen CD3E, epsilon polypeptide (TiT3 complex), antigen CD3G, gamma polypeptide, antigen CD3Z, zeta polypeptide, AW552088, Cd247, CD247 antigen, CD247 antigen, zeta subunit, Cd247 molecule, CD3, CD3 antigen delta chain, CD3 antigen delta polypeptide, CD3 antigen gamma chain, CD3 antigen, delta polypeptide, CD3 antigen, delta subunit, CD3 antigen, epsilon polypeptide, CD3 antigen, gamma polypeptide, CD3 antigen, zeta polypeptide, CD3 delta, CD3 epsilon, CD3 epsilon chain, CD3 epsilon subunit, CD3 epsilon subunit precursor, CD3 gamma-chain, CD3 glycoprotein, CD3 glycoprotein precursor, CD3 molecule delta polypeptide, CD3 molecule, delta, CD3 molecule, epsilon, CD3 molecule, epsilon polypeptide, CD3 molecule, gamma, CD3 molecule, gamma polypeptide, CD3 protein, CD3 TCR complex, CD3 type I transmembrane glycoprotein, CD3 type I transmembrane glycoprotein precursor, CD3 zeta chain, Cd3d, CD3D antigen delta, CD3D antigen, delta polypeptide (TiT3 complex), CD3d molecule, CD3d molecule, delta (CD3-TCR complex), CD3-DELTA, Cd3e, CD3E antigen, epsilon polypeptide, CD3E antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, CD3e molecule, epsilon (CD3-TCR complex), CD3epsilon, CD3-epsilon, Cd3-eta, Cd3g, CD3G antigen, gamma polypeptide, CD3g antigen, gamma polypeptide (TiT3 complex), CD3g molecule, CD3g molecule, epsilon (CD3-TCR complex), CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, Cd3h, CD3Q, Cd3z, CD3Z antigen, zeta polypeptide (TiT3 complex), Cd3zeta, Cd3-zeta, CD3zeta chain, CD3-zeta/eta, Ctg3, Ctg-3, FLJ18683, IMD17, IMD18, IMD19, IMD25, Leu-4, OKT3, delta chain, T cell antigen receptor complex epsilon subunit of T3, T3/TCR complex, T3d, T3e, T3g, T3Z, T-cell antigen receptor complex, epsilon subunit of T3, T-cell antigen receptor complex, gamma subunit of T3, T-cell antigen receptor complex, zeta subunit of CD3, T-cell receptor CD3 epsilon chain, T-cell receptor CD3 epsilon subunit, T-cell receptor CD3 subunit zeta, T-cell receptor CD3, subunit zeta, T-cell receptor T3 delta chain, T-cell receptor T3 eta chain, T-cell receptor T3 gamma chain, T-cell receptor T3 zeta chain, T-cell receptor zeta chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 gamma chain, T-cell surface glycoprotein CD3 zeta chain, T-cell surface protein, TcR CD3 delta-chain, TcR CD3 gamma-chain, TCR zeta chain, TCR zeta chain subunit, TCRE, Tcrk, TCRZ, TCRzeta, TiT3 complex, type I transmembrane protein, T-cell surface molecule CD3
Gene Symbols: Cd247, Cd3d, CD3E, CD3g
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Applications: Flow Cytometry
Conjugate: Brilliant Violet 605
Host Species: Mouse
Target Species: Human
Gene Accession No.: P04234, P07766, P09693, P20963
Gene ID (Entrez): 915, 916, 917, 919
Immunogen: __
Purification Method: Affinity chromatography
Gene: __
Antigen:
CD3
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
4930549J05Rik, A430104F18Rik, AI504783, antigen CD3D, delta polypeptide (TiT3 complex), antigen CD3E, epsilon polypeptide (TiT3 complex), antigen CD3G, gamma polypeptide, antigen CD3Z, zeta polypeptide, AW552088, Cd247, CD247 antigen, CD247 antigen, zeta subunit, Cd247 molecule, CD3, CD3 antigen delta chain, CD3 antigen delta polypeptide, CD3 antigen gamma chain, CD3 antigen, delta polypeptide, CD3 antigen, delta subunit, CD3 antigen, epsilon polypeptide, CD3 antigen, gamma polypeptide, CD3 antigen, zeta polypeptide, CD3 delta, CD3 epsilon, CD3 epsilon chain, CD3 epsilon subunit, CD3 epsilon subunit precursor, CD3 gamma-chain, CD3 glycoprotein, CD3 glycoprotein precursor, CD3 molecule delta polypeptide, CD3 molecule, delta, CD3 molecule, epsilon, CD3 molecule, epsilon polypeptide, CD3 molecule, gamma, CD3 molecule, gamma polypeptide, CD3 protein, CD3 TCR complex, CD3 type I transmembrane glycoprotein, CD3 type I transmembrane glycoprotein precursor, CD3 zeta chain, Cd3d, CD3D antigen delta, CD3D antigen, delta polypeptide (TiT3 complex), CD3d molecule, CD3d molecule, delta (CD3-TCR complex), CD3-DELTA, Cd3e, CD3E antigen, epsilon polypeptide, CD3E antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, CD3e molecule, epsilon (CD3-TCR complex), CD3epsilon, CD3-epsilon, Cd3-eta, Cd3g, CD3G antigen, gamma polypeptide, CD3g antigen, gamma polypeptide (TiT3 complex), CD3g molecule, CD3g molecule, epsilon (CD3-TCR complex), CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, Cd3h, CD3Q, Cd3z, CD3Z antigen, zeta polypeptide (TiT3 complex), Cd3zeta, Cd3-zeta, CD3zeta chain, CD3-zeta/eta, Ctg3, Ctg-3, FLJ18683, IMD17, IMD18, IMD19, IMD25, Leu-4, OKT3, delta chain, T cell antigen receptor complex epsilon subunit of T3, T3/TCR complex, T3d, T3e, T3g, T3Z, T-cell antigen receptor complex, epsilon subunit of T3, T-cell antigen receptor complex, gamma subunit of T3, T-cell antigen receptor complex, zeta subunit of CD3, T-cell receptor CD3 epsilon chain, T-cell receptor CD3 epsilon subunit, T-cell receptor CD3 subunit zeta, T-cell receptor CD3, subunit zeta, T-cell receptor T3 delta chain, T-cell receptor T3 eta chain, T-cell receptor T3 gamma chain, T-cell receptor T3 zeta chain, T-cell receptor zeta chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 gamma chain, T-cell surface glycoprotein CD3 zeta chain, T-cell surface protein, TcR CD3 delta-chain, TcR CD3 gamma-chain, TCR zeta chain, TCR zeta chain subunit, TCRE, Tcrk, TCRZ, TCRzeta, TiT3 complex, type I transmembrane protein, T-cell surface molecule CD3
Gene Symbols:
Cd247, Cd3d, CD3E, CD3g
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 605
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P04234, P07766, P09693, P20963
Gene ID (Entrez):
915, 916, 917, 919
Immunogen:
__
Purification Method:
Affinity chromatography
Gene:
__