200008464

IL-33R (ST2) Monoclonal Antibody (RMST2-2), Brilliant Ultra Violet™ 395, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IL-33R (ST2)

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols

IL1RL1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

RMST2-2

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 395

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P14719

Gene ID (Entrez)

17082

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Gene

IL1RL1

Description

  • IL-33R, also known as ST2, is a receptor for IL-33
  • It is a member of the IL-1 receptor family of innate receptors
  • Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33
  • IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways
  • This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13
  • Two most common isoforms of IL-33R that result from alternative splicing are ST2L – the membrane bound form, and ST2S – the soluble form
  • The membrane bound form can be released from the cell surface by proteolytic cleavage
  • The soluble forms have been suggested to act as decoys dampening the IL-33 signaling
  • IL-33R is primarily expressed by mast cells, basophils, and eosinophils
  • In mouse, IL-33R expression has been shown on ILC2 and Th2 cells
  • IL-33R signaling has been implicated in the number of immune conditions, including allergies, arthritis, atherosclerosis and sepsis.

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Fischer Scientific

200008464

Rat Monoclonal Antibody...


Antigen:
IL-33R (ST2)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols:
IL1RL1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
RMST2-2

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P14719

Gene ID (Entrez):
17082

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
IL1RL1

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200008474

Mouse Monoclonal Antibody...


Antigen:
CD206 (MMR)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4

Gene Symbols:
Mrc1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
19.2

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P22897

Gene ID (Entrez):
4360

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
Mrc1

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200008483

Mouse Monoclonal Antibody...


Antigen:
CD223 (LAG-3)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Gene Symbols:
LAG3

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
3DS223H

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P18627

Gene ID (Entrez):
3902

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
LAG3

Img

Fischer Scientific

200008489

Rat Monoclonal Antibody...


Antigen:
IL-33R (ST2)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols:
IL1RL1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
RMST2-2

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 615

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P14719

Gene ID (Entrez):
17082

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
IL1RL1