200020093

HLA-DRB1 Monoclonal Antibody (C3), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

HLA-DRB1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

Clone P2-beta-3, DR-16, DRB1, DRw10, DW2.2/DR2.2, HLA class II histocompatibility antigen, DR-1 beta chain, HLA class II histocompatibility antigen, DRB1-15 beta chain, HLA class II histocompatibility antigen, DRB1-16 beta chain, HLA class II histocompatibility antigen, DRB1-3 chain, HLA-DR1B, HLA-DRB, HLA-DRB1, HLA-DRB2, human leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface glycoprotein, MHC class II HLA-DRw10-beta, SS1

Gene Symbols

HLA-DRB1

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

HLA-DRB1

Clone

C3

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine, Rat

Gene Accession No.

P01911

Gene ID (Entrez)

3123

Immunogen

Recombinant Human HLA-DRB1 protein, Gly30-Ser266 (Accession #P01911)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • HLA-DRA is one of the HLA class II alpha chain paralogues
  • This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The alpha chain is approximately 33-35 kDa and its gene contains 5 exons
  • Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail
  • DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

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Img

Fischer Scientific

200020093

Mouse Monoclonal Antibody...


Antigen:
HLA-DRB1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Clone P2-beta-3, DR-16, DRB1, DRw10, DW2.2/DR2.2, HLA class II histocompatibility antigen, DR-1 beta chain, HLA class II histocompatibility antigen, DRB1-15 beta chain, HLA class II histocompatibility antigen, DRB1-16 beta chain, HLA class II histocompatibility antigen, DRB1-3 chain, HLA-DR1B, HLA-DRB, HLA-DRB1, HLA-DRB2, human leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface glycoprotein, MHC class II HLA-DRw10-beta, SS1

Gene Symbols:
HLA-DRB1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
HLA-DRB1

Clone:
C3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine, Rat

Gene Accession No.:
P01911

Gene ID (Entrez):
3123

Immunogen:
Recombinant Human HLA-DRB1 protein, Gly30-Ser266 (Accession #P01911)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020094

Rabbit Polyclonal Antibody...


Antigen:
CD64

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AI323638, AV092959, CD64, CD64 antigen, CD64A, Fc fragment of IgG high affinity Ib receptor, Fc fragment of IgG receptor Ia, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64), Fc fragment of IgG, high affinity Ib, receptor for (CD64), Fc gamma receptor, Fc gamma receptor Ia, Fc receptor, IgG, high affinity I, Fcg1, Fc-gamma receptor 1, Fc-gamma receptor I A1, Fc-gamma RI, Fc-gamma RIA, FcgammaRI, FcgammaRIa, Fcgr1, FCGR1A, Fcgr1b, FcgRI, FCRI, FLJ18345, high affinity IgG Fc receptor, subunit beta, high affinity immunoglobulin gamma Fc receptor I, high-affinity immunoglobulin gamma Fc receptor I, IGFR1, IgG Fc receptor I, IgG high affinity Fc receptor, IGGHAFC, RP11-196G18.2

Gene Symbols:
Fcgr1, FCGR1A

Isotype:
IgG

Purification Method:
Protein A

Gene:
FCGR1A

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P12314, P26151

Gene ID (Entrez):
14129, 2209

Immunogen:
Recombinant Mouse CD64 protein, Val73-Ser294 (Accession #P26151)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020094

Rabbit Polyclonal Antibody...


Antigen:
CD64

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AI323638, AV092959, CD64, CD64 antigen, CD64A, Fc fragment of IgG high affinity Ib receptor, Fc fragment of IgG receptor Ia, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64), Fc fragment of IgG, high affinity Ib, receptor for (CD64), Fc gamma receptor, Fc gamma receptor Ia, Fc receptor, IgG, high affinity I, Fcg1, Fc-gamma receptor 1, Fc-gamma receptor I A1, Fc-gamma RI, Fc-gamma RIA, FcgammaRI, FcgammaRIa, Fcgr1, FCGR1A, Fcgr1b, FcgRI, FCRI, FLJ18345, high affinity IgG Fc receptor, subunit beta, high affinity immunoglobulin gamma Fc receptor I, high-affinity immunoglobulin gamma Fc receptor I, IGFR1, IgG Fc receptor I, IgG high affinity Fc receptor, IGGHAFC, RP11-196G18.2

Gene Symbols:
Fcgr1, FCGR1A

Isotype:
IgG

Purification Method:
Protein A

Gene:
FCGR1A

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P12314, P26151

Gene ID (Entrez):
14129, 2209

Immunogen:
Recombinant Mouse CD64 protein, Val73-Ser294 (Accession #P26151)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020095

Mouse Monoclonal Antibody...


Antigen:
Afamin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Afamin, AFM, ALB2, ALBA, Alf, alpha albumin, alpha-Alb, Alpha-albumin, MGC125338, MGC125339

Gene Symbols:
AFM

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
AFM

Clone:
C1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
P36953

Gene ID (Entrez):
282708

Immunogen:
Recombinant Rat AFM protein, Leu22-Tyr201 (Accession #P36953)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.