200020106

BACE2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

BACE2

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

Q6IE75, Q9JL18, Q9Y5Z0

Gene ID (Entrez)

25825, 288227, 56175

Immunogen

Recombinant Rat BACE2 protein, Gly242-Val502 (Accession #Q6IE75)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

1110059C24Rik, 56 kDa aspartic-like protease, AEPLC, AI850424, ALP56, ARP1, asp 1, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, Bace2, BAE2, be, beta secretase 2, Beta-secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, CDA13, CEAP1, Down region aspartic protease, Down syndrome region aspartic protease, DRAP, memapsin 1, memapsin-1, Membrane-associated aspartic protease 1, theta-secretase, transmembrane aspartic proteinase Asp1, UNQ418/PRO852

Gene Symbols

BACE2

Isotype

IgG

Purification Method

Protein A

Gene

BACE2

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Description

  • BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP)
  • BACE2 cleaves APP between residues 690 and 691
  • This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP
  • BACE2 is also know to cleave APP between residues 671 and 672
  • Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.

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Img

Fischer Scientific

200020106

Rabbit Polyclonal Antibody...


Antigen:
BACE2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q6IE75, Q9JL18, Q9Y5Z0

Gene ID (Entrez):
25825, 288227, 56175

Immunogen:
Recombinant Rat BACE2 protein, Gly242-Val502 (Accession #Q6IE75)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1110059C24Rik, 56 kDa aspartic-like protease, AEPLC, AI850424, ALP56, ARP1, asp 1, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, Bace2, BAE2, be, beta secretase 2, Beta-secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, CDA13, CEAP1, Down region aspartic protease, Down syndrome region aspartic protease, DRAP, memapsin 1, memapsin-1, Membrane-associated aspartic protease 1, theta-secretase, transmembrane aspartic proteinase Asp1, UNQ418/PRO852

Gene Symbols:
BACE2

Isotype:
IgG

Purification Method:
Protein A

Gene:
BACE2

Img

Fischer Scientific

200020107

Mouse Monoclonal Antibody...


Antigen:
Ferroportin

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
Q9JHI9, Q9NP59

Gene ID (Entrez):
30061, 53945

Immunogen:
Recombinant Human FPN protein, Trp127-Val321 (Accession #Q9NP59)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
CAR1, Cell adhesion regulator, duodenal-specific, Dusg, Ferroportin, ferroportin 1, ferroportin-1, Fpn1, Fpt1, HFE4, IREG1, iron regulated gene 1, iron-regulated transporter 1, Metal transporter protein 1, metal transporting protein 1, MST079, MSTP079, MTP, MTP1, Ol5, Pcm, polycythaemia, Slc11a3, SLC11A3 iron transporter, Slc39a1, Slc40a1, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3, solute carrier family 39 (iron-regulated transporter), member 1, solute carrier family 40 (iron-regulated transporter), member 1, solute carrier family 40 member 1

Gene Symbols:
SLC40A1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
SLC40A1

Img

Fischer Scientific

200020107

Mouse Monoclonal Antibody...


Antigen:
Ferroportin

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
Q9JHI9, Q9NP59

Gene ID (Entrez):
30061, 53945

Immunogen:
Recombinant Human FPN protein, Trp127-Val321 (Accession #Q9NP59)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
CAR1, Cell adhesion regulator, duodenal-specific, Dusg, Ferroportin, ferroportin 1, ferroportin-1, Fpn1, Fpt1, HFE4, IREG1, iron regulated gene 1, iron-regulated transporter 1, Metal transporter protein 1, metal transporting protein 1, MST079, MSTP079, MTP, MTP1, Ol5, Pcm, polycythaemia, Slc11a3, SLC11A3 iron transporter, Slc39a1, Slc40a1, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3, solute carrier family 39 (iron-regulated transporter), member 1, solute carrier family 40 (iron-regulated transporter), member 1, solute carrier family 40 member 1

Gene Symbols:
SLC40A1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
SLC40A1

Img

Fischer Scientific

200020107

Mouse Monoclonal Antibody...


Antigen:
Ferroportin

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
Q9JHI9, Q9NP59

Gene ID (Entrez):
30061, 53945

Immunogen:
Recombinant Human FPN protein, Trp127-Val321 (Accession #Q9NP59)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
CAR1, Cell adhesion regulator, duodenal-specific, Dusg, Ferroportin, ferroportin 1, ferroportin-1, Fpn1, Fpt1, HFE4, IREG1, iron regulated gene 1, iron-regulated transporter 1, Metal transporter protein 1, metal transporting protein 1, MST079, MSTP079, MTP, MTP1, Ol5, Pcm, polycythaemia, Slc11a3, SLC11A3 iron transporter, Slc39a1, Slc40a1, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3, solute carrier family 39 (iron-regulated transporter), member 1, solute carrier family 40 (iron-regulated transporter), member 1, solute carrier family 40 member 1

Gene Symbols:
SLC40A1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
SLC40A1