200020112

GP6 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

GP6

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Porcine

Gene Accession No.

Q9HCN6

Gene ID (Entrez)

100517829, 51206

Immunogen

Recombinant Human GP6 protein, Tyr86-Thr231 (Accession #Q9HCN6)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

9830166G18Rik, BDPLT11, Glycoprotein 5, glycoprotein 6, glycoprotein 6 (platelet), glycoprotein VI (platelet), glycoprotein VI platelet, Gm469, GP6, GPIV, GPVI, platelet collagen receptor, platelet glycoprotein VI

Gene Symbols

GP6

Isotype

IgG

Purification Method

Protein A

Gene

GP6

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Description

  • Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets
  • Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets
  • Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels
  • Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation
  • In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss
  • However, exposure of collagen after rupture of atherosclerotic plaques is a major stimulus of thrombus formation associated with myocardial infarction or stroke.

Compare Similar Items

Show Difference

Img

Fischer Scientific

200020112

Rabbit Polyclonal Antibody...


Antigen:
GP6

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Porcine

Gene Accession No.:
Q9HCN6

Gene ID (Entrez):
100517829, 51206

Immunogen:
Recombinant Human GP6 protein, Tyr86-Thr231 (Accession #Q9HCN6)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
9830166G18Rik, BDPLT11, Glycoprotein 5, glycoprotein 6, glycoprotein 6 (platelet), glycoprotein VI (platelet), glycoprotein VI platelet, Gm469, GP6, GPIV, GPVI, platelet collagen receptor, platelet glycoprotein VI

Gene Symbols:
GP6

Isotype:
IgG

Purification Method:
Protein A

Gene:
GP6

Img

Fischer Scientific

200020113

Mouse Monoclonal Antibody...


Antigen:
VNN1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
O95497, Q9BDJ5

Gene ID (Entrez):
397246, 8876

Immunogen:
Recombinant Human VNN1 protein, Leu36-Leu223 (Accession #O95497)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
HDLCQ8, Pantetheinase, pantetheine hydrolase, Tiff66, V-1, vanin 1, Vanin1, vanin-1, vannin 1, vascular non-inflammatory molecule 1, VNN1

Gene Symbols:
VNN1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
VNN1

Img

Fischer Scientific

200020113

Mouse Monoclonal Antibody...


Antigen:
VNN1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
O95497, Q9BDJ5

Gene ID (Entrez):
397246, 8876

Immunogen:
Recombinant Human VNN1 protein, Leu36-Leu223 (Accession #O95497)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
HDLCQ8, Pantetheinase, pantetheine hydrolase, Tiff66, V-1, vanin 1, Vanin1, vanin-1, vannin 1, vascular non-inflammatory molecule 1, VNN1

Gene Symbols:
VNN1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
VNN1

Img

Fischer Scientific

200020116

Mouse Monoclonal Antibody...


Antigen:
VNN1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
O95497, Q9BDJ5

Gene ID (Entrez):
397246, 8876

Immunogen:
Recombinant Human VNN1 protein, Gln22-Gly491 (Accession #O95497)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
HDLCQ8, Pantetheinase, pantetheine hydrolase, Tiff66, V-1, vanin 1, Vanin1, vanin-1, vannin 1, vascular non-inflammatory molecule 1, VNN1

Gene Symbols:
VNN1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
VNN1