200020124

IL-15 Monoclonal Antibody (C6), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IL-15

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

AI503618, il 15, Il15, IL-15, ILN, Interleukin, interleukin 15, Interleukin15, interleukin-15, MGC9721, M-IL-15

Gene Symbols

IL15

Isotype

IgG κ

Purification Method

Protein A/G

Gene

IL15

Clone

C6

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine

Gene Accession No.

P40933, Q95253

Gene ID (Entrez)

3600, 397683

Immunogen

Recombinant Human IL15 protein, Trp50-Ser162 (Accession #P40933)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation
  • IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity
  • The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2
  • IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6
  • In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis
  • IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules
  • As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases
  • Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases
  • Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.

Compare Similar Items

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Img

Fischer Scientific

200020124

Mouse Monoclonal Antibody...


Antigen:
IL-15

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AI503618, il 15, Il15, IL-15, ILN, Interleukin, interleukin 15, Interleukin15, interleukin-15, MGC9721, M-IL-15

Gene Symbols:
IL15

Isotype:
IgG κ

Purification Method:
Protein A/G

Gene:
IL15

Clone:
C6

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P40933, Q95253

Gene ID (Entrez):
3600, 397683

Immunogen:
Recombinant Human IL15 protein, Trp50-Ser162 (Accession #P40933)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020125

Mouse Monoclonal Antibody...


Antigen:
TMPRSS2

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
D16Ertd61e, EC 3.4.219, epitheliasin, FLJ41954, MGC6821, Plasmic transmembrane protein X, PP9284, PRSS10, Serine protease 10, Tmprss2, TMPS2, Transmembrane protease serine 2, Transmembrane protease serine 2 catalytic chain, Transmembrane protease serine 2 non-catalytic chain, transmembrane protease, serine 2

Gene Symbols:
TMPRSS2

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Gene:
TMPRSS2

Clone:
C1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O15393

Gene ID (Entrez):
7113

Immunogen:
Recombinant Human TMPRSS2 protein, Ser284-Gly492 (Accession #O15393)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020126

Rabbit Polyclonal Antibody...


Antigen:
S100A7

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AY465109, Gm1020, NICE-2, protein S100-A15A, Protein S100-A7, protein S100-A7A, PSOR1, Psoriasin, psoriasin 1, S100 calcium binding protein A15, S100 calcium binding protein A7, S100 calcium binding protein A7A, S100 calcium binding protein A7-like 1, S100 calcium-binding protein A15, S100 calcium-binding protein A15A, S100 calcium-binding protein A7, S100 calcium-binding protein A7 (psoriasin 1), S100 calcium-binding protein A7A, S100 calcium-binding protein A7-like 1, S100A15, S100a15a, S100a17l1, S100A7, S100a7a, S100A7c, S100A7f, S100A7L1

Gene Symbols:
S100A7

Isotype:
IgG

Purification Method:
Protein A

Gene:
S100A7

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Bovine

Gene Accession No.:
Q28050

Gene ID (Entrez):
282344

Immunogen:
Recombinant Bovine S100A7 protein, Met1-Gln101 (Accession #Q28050)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020129

Rabbit Polyclonal Antibody...


Antigen:
S100A7

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AY465109, Gm1020, NICE-2, protein S100-A15A, Protein S100-A7, protein S100-A7A, PSOR1, Psoriasin, psoriasin 1, S100 calcium binding protein A15, S100 calcium binding protein A7, S100 calcium binding protein A7A, S100 calcium binding protein A7-like 1, S100 calcium-binding protein A15, S100 calcium-binding protein A15A, S100 calcium-binding protein A7, S100 calcium-binding protein A7 (psoriasin 1), S100 calcium-binding protein A7A, S100 calcium-binding protein A7-like 1, S100A15, S100a15a, S100a17l1, S100A7, S100a7a, S100A7c, S100A7f, S100A7L1

Gene Symbols:
S100a15a

Isotype:
IgG

Purification Method:
Protein A

Gene:
S100a15a

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
Q6S5I3

Gene ID (Entrez):
381493

Immunogen:
Recombinant Mouse S100A7 protein, Met1-Tyr108 (Accession #Q6S5I3)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.