200020317
Nephrin Monoclonal Antibody (C14), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Nephrin
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
CNF, Nephrin, nephrin 1, NephrinB, nephrosis 1 homolog, nephrin, nephrosis 1, congenital, Finnish type (nephrin), nephrosis 1, nephrin, NPHN, NPHS1, NPHS1 nephrin, NPHS1, nephrin, renal glomerulus-specific cell adhesion receptor
Gene Symbols
Nphs1
Isotype
IgG2b κ
Purification Method
Protein A/G
Gene
Nphs1
Clone
C14
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Mouse, Rat
Gene Accession No.
O60500, Q9QZS7, Q9R044
Gene ID (Entrez)
4868, 54631, 64563
Immunogen
Recombinant Human NPHN protein, Arg1160-Val1241 (Accession #O60500)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease
- Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss
- Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2
- Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process
- Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier
- Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis
- Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria
- The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling
- Nephrin seems to play a role in the development or function of the kidney glomerular filtration barrier and it may anchor the podocyte slit diaphragm to the actin cytoskeleton.
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Antigen: Nephrin
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: CNF, Nephrin, nephrin 1, NephrinB, nephrosis 1 homolog, nephrin, nephrosis 1, congenital, Finnish type (nephrin), nephrosis 1, nephrin, NPHN, NPHS1, NPHS1 nephrin, NPHS1, nephrin, renal glomerulus-specific cell adhesion receptor
Gene Symbols: Nphs1
Isotype: IgG2b κ
Purification Method: Protein A/G
Gene: Nphs1
Clone: C14
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse, Rat
Gene Accession No.: O60500, Q9QZS7, Q9R044
Gene ID (Entrez): 4868, 54631, 64563
Immunogen: Recombinant Human NPHN protein, Arg1160-Val1241 (Accession #O60500)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
Nephrin
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
CNF, Nephrin, nephrin 1, NephrinB, nephrosis 1 homolog, nephrin, nephrosis 1, congenital, Finnish type (nephrin), nephrosis 1, nephrin, NPHN, NPHS1, NPHS1 nephrin, NPHS1, nephrin, renal glomerulus-specific cell adhesion receptor
Gene Symbols:
Nphs1
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Gene:
Nphs1
Clone:
C14
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse, Rat
Gene Accession No.:
O60500, Q9QZS7, Q9R044
Gene ID (Entrez):
4868, 54631, 64563
Immunogen:
Recombinant Human NPHN protein, Arg1160-Val1241 (Accession #O60500)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: SERPINB4
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: 1110001H02Rik, 1110013A16Rik, LEUPIN, Leupin SERPINB4, Peptidase inhibitor 11, PI11, PI-11, protease inhibitor (leucine-serpin), RGD1562868, SCCA1, SCCA2, SCCA-2, SCCA2/SCCA1 fusion protein, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4, serine peptidase inhibitor, clade B, member 3A, serpin B4, serpin family B member 4, serpin peptidase inhibitor, clade B (ovalbumin), member 4, Serpinb3a, SERPINB4, Sqn5, squamous cell carcinoma antigen 1, squamous cell carcinoma antigen 2
Gene Symbols: Serpinb3a, SERPINB4
Isotype: IgG
Purification Method: Protein A
Gene: SERPINB4
Clone: __
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P48594
Gene ID (Entrez): 20248, 6318
Immunogen: Recombinant Mouse SERPINB4 protein, Asn60-Leu222 (Accession #Q9Z2G2)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
SERPINB4
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
1110001H02Rik, 1110013A16Rik, LEUPIN, Leupin SERPINB4, Peptidase inhibitor 11, PI11, PI-11, protease inhibitor (leucine-serpin), RGD1562868, SCCA1, SCCA2, SCCA-2, SCCA2/SCCA1 fusion protein, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4, serine peptidase inhibitor, clade B, member 3A, serpin B4, serpin family B member 4, serpin peptidase inhibitor, clade B (ovalbumin), member 4, Serpinb3a, SERPINB4, Sqn5, squamous cell carcinoma antigen 1, squamous cell carcinoma antigen 2
Gene Symbols:
Serpinb3a, SERPINB4
Isotype:
IgG
Purification Method:
Protein A
Gene:
SERPINB4
Clone:
__
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P48594
Gene ID (Entrez):
20248, 6318
Immunogen:
Recombinant Mouse SERPINB4 protein, Asn60-Leu222 (Accession #Q9Z2G2)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: SERPINB4
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: 1110001H02Rik, 1110013A16Rik, LEUPIN, Leupin SERPINB4, Peptidase inhibitor 11, PI11, PI-11, protease inhibitor (leucine-serpin), RGD1562868, SCCA1, SCCA2, SCCA-2, SCCA2/SCCA1 fusion protein, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4, serine peptidase inhibitor, clade B, member 3A, serpin B4, serpin family B member 4, serpin peptidase inhibitor, clade B (ovalbumin), member 4, Serpinb3a, SERPINB4, Sqn5, squamous cell carcinoma antigen 1, squamous cell carcinoma antigen 2
Gene Symbols: Serpinb3a, SERPINB4
Isotype: IgG
Purification Method: Protein A
Gene: SERPINB4
Clone: __
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P48594
Gene ID (Entrez): 20248, 6318
Immunogen: Recombinant Mouse SERPINB4 protein, Asn60-Leu222 (Accession #Q9Z2G2)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
SERPINB4
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
1110001H02Rik, 1110013A16Rik, LEUPIN, Leupin SERPINB4, Peptidase inhibitor 11, PI11, PI-11, protease inhibitor (leucine-serpin), RGD1562868, SCCA1, SCCA2, SCCA-2, SCCA2/SCCA1 fusion protein, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4, serine peptidase inhibitor, clade B, member 3A, serpin B4, serpin family B member 4, serpin peptidase inhibitor, clade B (ovalbumin), member 4, Serpinb3a, SERPINB4, Sqn5, squamous cell carcinoma antigen 1, squamous cell carcinoma antigen 2
Gene Symbols:
Serpinb3a, SERPINB4
Isotype:
IgG
Purification Method:
Protein A
Gene:
SERPINB4
Clone:
__
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P48594
Gene ID (Entrez):
20248, 6318
Immunogen:
Recombinant Mouse SERPINB4 protein, Asn60-Leu222 (Accession #Q9Z2G2)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: SEMA5B
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: AI893641, Kiaa1445, mKIAA1445, sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B, sema G, Sema5b, Semag, semaphorin 5B, semaphorin-5B, Semaphorin-G, SemG, UNQ5867/PRO34001
Gene Symbols: SEMA5B
Isotype: IgG
Purification Method: Protein A
Gene: SEMA5B
Clone: __
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse, Porcine, Rat
Gene Accession No.: Q60519, Q9P283
Gene ID (Entrez): 100519925, 20357, 303901, 54437
Immunogen: Recombinant Human SEMA5B protein, Leu36-Pro602 (Accession #Q9P283)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
SEMA5B
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
AI893641, Kiaa1445, mKIAA1445, sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B, sema G, Sema5b, Semag, semaphorin 5B, semaphorin-5B, Semaphorin-G, SemG, UNQ5867/PRO34001
Gene Symbols:
SEMA5B
Isotype:
IgG
Purification Method:
Protein A
Gene:
SEMA5B
Clone:
__
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse, Porcine, Rat
Gene Accession No.:
Q60519, Q9P283
Gene ID (Entrez):
100519925, 20357, 303901, 54437
Immunogen:
Recombinant Human SEMA5B protein, Leu36-Pro602 (Accession #Q9P283)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.