200020422

SIGLEC7 Monoclonal Antibody (D5), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

SIGLEC7

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

Adhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM1, AIRM-1, CD328, CDw328, D-siglec, p75, p75/ AIRM-1, p75/AIRM1, QA79, QA79 membrane protein, sialic acid binding Ig like lectin 7, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec, SIGLEC19P, SIGLEC7, SIGLEC-7, SIGLECP2

Gene Symbols

SIGLEC7

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

SIGLEC7

Clone

D5

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Rat

Gene Accession No.

Q9Y286

Gene ID (Entrez)

27036

Immunogen

Recombinant Human SIGLEC7 protein, Gln19-Ser336 (Accession #Q9Y286)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Putative adhesion molecule that mediates sialic-acid dependent binding to cells
  • Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid
  • Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide)
  • The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
  • In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules
  • Mediates inhibition of natural killer cells cytotoxicity
  • May play a role in hemopoiesis
  • Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).

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Img

Fischer Scientific

200020422

Mouse Monoclonal Antibody...


Antigen:
SIGLEC7

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Adhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM1, AIRM-1, CD328, CDw328, D-siglec, p75, p75/ AIRM-1, p75/AIRM1, QA79, QA79 membrane protein, sialic acid binding Ig like lectin 7, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec, SIGLEC19P, SIGLEC7, SIGLEC-7, SIGLECP2

Gene Symbols:
SIGLEC7

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
SIGLEC7

Clone:
D5

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
Q9Y286

Gene ID (Entrez):
27036

Immunogen:
Recombinant Human SIGLEC7 protein, Gln19-Ser336 (Accession #Q9Y286)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

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200020423

Mouse Monoclonal Antibody...


Antigen:
S100A8

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
60B8AG, AI323541, B8Ag, CAGA, CAGB, calgranulin A, calgranulin B, calgranulin-A, Calgranulin-B, calprotectin L1H subunit, Calprotectin L1L subunit, CFAg, CGLA, CGLB, chemotactic cytokine CP-10, chemotactic S100 protein, CP-10, Cystic fibrosis antigen, L1Ag, leukocyte L1 complex heavy chain, Leukocyte L1 complex light chain, LIAG, MA387, MAC387, MIF, Migration inhibitory factor-related protein 14, migration inhibitory factor-related protein 8, MRP14, MRP-14, MRP8, MRP-8, NIF, P14, p8, Pro-inflammatory S100 cytokine, protein S100-A8, Protein S100-A9, S100 A8, S100 calcium binding protein A8, S100 calcium binding protein A8 (calgranulin A), S100 calcium binding protein A9, S100 calcium-binding protein A8, S100 calcium-binding protein A8 (calgranulin A), S100 calcium-binding protein A9, S100 calcium-binding protein A9 (calgranulin B), S100A8, S100A9, Urinary stone protein band A

Gene Symbols:
S100A8

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
S100A8

Clone:
C6

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
P05109, P27005

Gene ID (Entrez):
20201, 6279

Immunogen:
Recombinant Human S100A8 protein, Met1-Glu93 (Accession #P05109)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020424

Mouse Monoclonal Antibody...


Antigen:
S100A9

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
60B8AG, AW546964, BEE22, BM-009, Cagb, calgranulin B, calgranulin-B, Calprotectin L1H subunit, CFAG, CGLB, DKFZp686B04128, GAGB, intracellular calcium-binding protein (MRP14), L1AG, Leukocyte L1 complex heavy chain, LIAG, MAC387, Macrophage, MIF, Migration inhibitory factor-related protein 14, Monocyte, MRP14, MRP-14, MRP15, MRP16, myeloid-related protein 14, NIF, P14, protein S100-A9, S100 A9, S100 calcium binding protein A9, S100 calcium binding protein A9 (calgranulin B), S100 calcium-binding protein A9, S100 calcium-binding protein A9 (calgranulin B), S100a9

Gene Symbols:
S100A9

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
S100A9

Clone:
H5

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P06702

Gene ID (Entrez):
100127489, 6280

Immunogen:
Recombinant Human S100A9 protein, Met1-Pro114 (Accession #P06702)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020426

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Antigen:
GC

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
DBP, DBP/ VDBG, DBP/GC, DBP02, DBP-maf, epididymis secretory protein Li 51, Gc, Gc globulin, Gc protein-derived macrophage activating factor, GC, vitamin D binding protein, gc-globulin, GcMAF, Gc-MAF, GRD3, group specific component, Group specific component vitamin D binding protein, Group-specific component, group-specific component (vitamin D binding protein), hDBP, HEL-S-51, V VDB, VDB, VDBG, Vdbp, Vitamin D binding alpha globulin, vitamin D-binding alpha-globulin, vitamin D-binding protein, Vitamin D-binding protein-macrophage activating factor

Gene Symbols:
GC

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
GC

Clone:
D4

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P02774

Gene ID (Entrez):
2638

Immunogen:
Recombinant Human DBP protein, Leu209-Asp401 (Accession #P02774)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.