200020429

CD127 Monoclonal Antibody (D6), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD127

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

CD127, CD127 antigen, CDW127, IL 7 receptor, IL 7R a, IL 7R subunit alpha, IL 7R a, IL 7Ra, IL 7Ra, IL7 receptor, IL-7 receptor alpha chain, IL7 receptor subunit alpha, IL-7 receptor subunit alpha, IL7R, IL-7R, IL7R a, IL7R alpha, IL7R subunit alpha, IL-7R subunit alpha, IL7R a, IL7RA, IL-7RA, IL-7Ralpha, IL-7R-alpha, IL7Ra, ILRA, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, Interleukin7 receptor subunit alpha, interleukin-7 receptor subunit alpha, MGC107557, sCD127, soluble IL 7 receptor, soluble IL 7R

Gene Symbols

Il7r

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

Il7r

Clone

D6

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P16871

Gene ID (Entrez)

3575

Immunogen

Recombinant Eukaryotic Human IL7R protein, Glu21-Asp239 (Accession #P16871)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis
  • The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer
  • CD127 consists of an alpha chain and a gamma chain
  • The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules
  • CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells
  • The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor
  • Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency.

Compare Similar Items

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Img

Fischer Scientific

200020429

Mouse Monoclonal Antibody...


Antigen:
CD127

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
CD127, CD127 antigen, CDW127, IL 7 receptor, IL 7R a, IL 7R subunit alpha, IL 7R a, IL 7Ra, IL 7Ra, IL7 receptor, IL-7 receptor alpha chain, IL7 receptor subunit alpha, IL-7 receptor subunit alpha, IL7R, IL-7R, IL7R a, IL7R alpha, IL7R subunit alpha, IL-7R subunit alpha, IL7R a, IL7RA, IL-7RA, IL-7Ralpha, IL-7R-alpha, IL7Ra, ILRA, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, Interleukin7 receptor subunit alpha, interleukin-7 receptor subunit alpha, MGC107557, sCD127, soluble IL 7 receptor, soluble IL 7R

Gene Symbols:
Il7r

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
Il7r

Clone:
D6

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P16871

Gene ID (Entrez):
3575

Immunogen:
Recombinant Eukaryotic Human IL7R protein, Glu21-Asp239 (Accession #P16871)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020430

Mouse Monoclonal Antibody...


Antigen:
Cathepsin S

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Cat S, cathepsin S, Cats, CTSS

Gene Symbols:
CTSS

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
CTSS

Clone:
C1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
P25774, Q02765

Gene ID (Entrez):
1520, 50654

Immunogen:
Recombinant Human CTSS protein, Leu115-Ile331 (Accession #P25774)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020431

Mouse Monoclonal Antibody...


Antigen:
LRG1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1300008B03Rik, 2310031E04Rik, A2GL, HMFT1766, leucine rich alpha 2 glycoprotein, leucine rich alpha-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein, leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein precursor, LRG, LRG 1, LRG1, LRG-1, Lrhg

Gene Symbols:
LRG1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
LRG1

Clone:
C2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P02750

Gene ID (Entrez):
116844

Immunogen:
Recombinant Human LRG1 protein, Thr37-Leu340 (Accession #P02750)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020431

Mouse Monoclonal Antibody...


Antigen:
LRG1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1300008B03Rik, 2310031E04Rik, A2GL, HMFT1766, leucine rich alpha 2 glycoprotein, leucine rich alpha-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein, leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein precursor, LRG, LRG 1, LRG1, LRG-1, Lrhg

Gene Symbols:
LRG1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
LRG1

Clone:
C2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P02750

Gene ID (Entrez):
116844

Immunogen:
Recombinant Human LRG1 protein, Thr37-Leu340 (Accession #P02750)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.