Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
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GITR/TNFRSF18
1 mg/mL
Monoclonal
Purified
RUO
Mouse
Activation-inducible TNFR family receptor, AITRTNF receptor superfamily activation-inducible protein, CD357 antigen, GITR-D, GITRtumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, tumor necrosis factor receptor superfamily, member 18
This antibody was raised by immunising Wistar rats with the CD25+CD4+ T cell line. Hybridoma cells were generated by fusing spleen cells from the immunized rat with P3X63Ag8.653 myeloma cells, assessed for secreting antibodies capable of neutralizing in vitro CD25+CD4+ T cell-mediated suppression of anti-CD3-stimulated T cell proliferation9, and then cloned. This DTA-1 clone secreted a monoclonal rat immunoglobulin G2a (IgG2a) that showed high neutralizing activity.
Primary
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DTA-1
Western Blot, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Agonist Activity
Unconjugated
Rabbit
Apoptosis
PBS
8784
IgG λ
Protein A purified