22-158-014

Murine anti-PON1, Clone: KRJ1, ZeptoMetrix

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 22-158-014-Each-of-1 In Stock ₹ 1,94,734.56

22-158-014 - Each of 1

₹ 1,94,734.56

In Stock

Quantity

1

Base Price: ₹ 1,94,734.56

GST (18%): ₹ 35,052.221

Total Price: ₹ 2,29,786.781

Antigen

PON1

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1

Applications

Western Blot

Clone

KRJ1

Formulation

1mg in PBS. No preservatives added.

Immunogen

Partially purified PON1 from human plasma

Quantity

1 mg

Primary or Secondary

Primary

Content And Storage

Store at −10°C or below. Avoid freeze/thaw cycles. Thawed material may be stored at 4°C for short-term use.

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Description

  • PON1 (arylesterase/paraoxonase) is a polymorphic enzyme closely associated with high-density lipoproteins (HDL)
  • It is located on chromosome 7 along with 2 other paraoxanase genes, PON2 and PON3
  • It is a 355 amino acid, 43kDa glycoprotein produced in the liver and secreted into the bloodstream
  • Gene polymorphisms occur in both coding and non-coding regions
  • Two major polymorphisms in the coding region are L55M and Q192R
  • Q192R polymorphisms result in three major functional phenotypes Q/Q, Q/R and RR
  • PON1 hydrolyses organophosphates and prevents the oxidation of low-density lipoproteins (LDL)
  • It may inhibit the progression of atherosclerosis by inhibition of LDL oxidation
  • Levels of PON1 in serum vary among individuals and are decreased in chronic renal failure, liver cirrhosis, diabetes, peripheral neuropathy, and familial hypercholesterolemia.

Compare Similar Items

Show Difference

Img

Fischer Scientific

22-158-014

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Antigen:
PON1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1

Applications:
Western Blot

Clone:
KRJ1

Formulation:
1mg in PBS. No preservatives added.

Immunogen:
Partially purified PON1 from human plasma

Quantity:
1 mg

Primary or Secondary:
Primary

Content And Storage:
Store at −10°C or below. Avoid freeze/thaw cycles. Thawed material may be stored at 4°C for short-term use.

Img

Fischer Scientific

22-158-015

--


Antigen:
PON1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1

Applications:
Western Blot

Clone:
KRJ2

Formulation:
1mg in PBS. No preservatives added.

Immunogen:
Recombinant human PON1 produced in E. coli

Quantity:
1 mg

Primary or Secondary:
Primary

Content And Storage:
Store at −10°C or below. Avoid freeze/thaw cycles. Thawed material may be stored at 4°C for short-term use.

Img

ZeptoMetrix

22-158-019

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Antigen:
__

Classification:
__

Conjugate:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Target Species:
__

Isotype:
__

Applications:
__

Clone:
__

Formulation:
__

Immunogen:
__

Quantity:
6 x 0.125 mL Vials

Primary or Secondary:
__

Content And Storage:
2°C to 8°C

Img

ZeptoMetrix

22-158-022

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Antigen:
__

Classification:
__

Conjugate:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Target Species:
__

Isotype:
__

Applications:
__

Clone:
__

Formulation:
__

Immunogen:
__

Quantity:
6 x 0.125 mL Vials

Primary or Secondary:
__

Content And Storage:
2°C to 8°C