25-932-280

PLZF Monoclonal Antibody (9E12), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 25-932-280-Each-of-1 In Stock ₹ 18,652.08

25-932-280 - Each of 1

₹ 18,652.08

In Stock

Quantity

1

Base Price: ₹ 18,652.08

GST (18%): ₹ 3,357.374

Total Price: ₹ 22,009.454

Antigen

PLZF

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q05516

Gene Symbols

ZBTB16

Immunogen

PLFZ peptide

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry

Clone

9E12

Conjugate

PE-Cyanine7

Gene

ZBTB16

Gene Alias

AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145

Host Species

Armenian Hamster

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

235320, 7704

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • This 9E12 monoclonal antibody reacts with human and mouse promyelocytic leukemia zinc finger (PLZF), a member of the BTB-POZ family of transcription factors
  • Expression of this transcriptional repressor in immune cells differs between mice and humans
  • In mice, PLZF is highly expressed in immature CD1d-resricted NKT2 and NKT1 cells, and a subset of gamma delta (Vg1.1+Vd6.3+) T cells
  • Studies have also demonstrated expression of PLZF in non-invariant CD1d-restricted T cells, as well as non-CD1d-restricted innate T cells
  • In humans, PLZF is expressed in NK cells, gamma delta T cells, as well as CD4 and CD8+ T cells
  • PLZF is also expressed in MR1-specific mucosal-associated invariant T cells, as well as in MHC Class II-restricted T cells that develop via a thymocyte-thymocyte interaction in humans
  • PLZF is expressed by innate lymphoid cells and its progenitor cells
  • PLZF exists as a homodimer or in complex with PLZP, and has been shown to be involved in the development of NKT cells, NK cell function, cellular quiescence, growth suppression, and maintece of homeostatis
  • Finally, PLZF has been shown to inhibit gene expression induced by retinoic acid receptor
  • This 9E12 antibody stains mouse thymocytes brighter than Mags.21F7
  • This 9E12 antibody has been tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcription Factor Staining Buffer Set (cat
  • 00-5523) and protocol
  • This can be used at less than or equal to 0
  • This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus
  • This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase
  • Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL)
  • Alternate transcriptional splice variants have been characterized.

Compare Similar Items

Show Difference

Img

Fischer Scientific

25-932-280

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Antigen:
PLZF

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q05516

Gene Symbols:
ZBTB16

Immunogen:
PLFZ peptide

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
9E12

Conjugate:
PE-Cyanine7

Gene:
ZBTB16

Gene Alias:
AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145

Host Species:
Armenian Hamster

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
235320, 7704

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

25-932-282

--


Antigen:
PLZF

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q05516

Gene Symbols:
ZBTB16

Immunogen:
PLFZ peptide

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
9E12

Conjugate:
PE-Cyanine7

Gene:
ZBTB16

Gene Alias:
AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145

Host Species:
Armenian Hamster

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
235320, 7704

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

25-947-580

--


Antigen:
ID2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P41136, Q02363

Gene Symbols:
ID2

Immunogen:
Purified recombinant fragment of human ID2, corresponding to amino acids 1-134 expressed in E. coli

Quantity:
25μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
ILCID2

Conjugate:
PE-Cyanine7

Gene:
ID2

Gene Alias:
Ac2-300; AI255428; bHLHb26; C78922; cell growth-inhibiting gene 8; class B basic helix-loop-helix protein 26; DNA-binding protein inhibitor ID2; DNA-binding protein inhibitor ID-2; GIG8; helix-loop-helix protein ID2; Id2; Id-2; ID2A; ID2H; Idb2; Inhibitor of differentiation 2; inhibitor of DNA binding 2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; inhibitor of DNA binding 2, HLH protein; MGC26389; OTTHUMP00000140258; OTTHUMP00000200297

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15902, 3398

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

25-947-582

--


Antigen:
ID2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P41136, Q02363

Gene Symbols:
ID2

Immunogen:
Purified recombinant fragment of human ID2, corresponding to amino acids 1-134 expressed in E. coli

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
ILCID2

Conjugate:
PE-Cyanine7

Gene:
ID2

Gene Alias:
Ac2-300; AI255428; bHLHb26; C78922; cell growth-inhibiting gene 8; class B basic helix-loop-helix protein 26; DNA-binding protein inhibitor ID2; DNA-binding protein inhibitor ID-2; GIG8; helix-loop-helix protein ID2; Id2; Id-2; ID2A; ID2H; Idb2; Inhibitor of differentiation 2; inhibitor of DNA binding 2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; inhibitor of DNA binding 2, HLH protein; MGC26389; OTTHUMP00000140258; OTTHUMP00000200297

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15902, 3398

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid