35-150-0Z

NPC1 Monoclonal Antibody (17B5), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 35-150-0Z-Each-of-1 In Stock ₹ 38,502.00

35-150-0Z - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

NPC1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

O15118

Gene Symbols

NPC1

Immunogen

Fragments of Human NPC1 conjugated to a carrier protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

17B5

Conjugate

Unconjugated

Gene

NPC1

Gene Alias

A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4864

Content And Storage

-20°C

Form

Liquid

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Description

  • Mutations in the Niemann-Pick disease type C1 (NPC1) gene result in a fatal progressive neurodegenerative disorder characterized by an abnormal sequestration of lipids including cholesterol and glycosphingolipids
  • The NPC1 protein is a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain
  • NPC1 transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolyzed and released as free cholesterol
  • NPC1, in addition to FTO, MC4R, and PTER has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations.

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Invitrogen

35-150-0Z

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Antigen:
NPC1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
O15118

Gene Symbols:
NPC1

Immunogen:
Fragments of Human NPC1 conjugated to a carrier protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
17B5

Conjugate:
Unconjugated

Gene:
NPC1

Gene Alias:
A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4864

Content And Storage:
-20°C

Form:
Liquid

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Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
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Gene Symbols:
CASP3

Immunogen:
Full length, recombinant human caspase 3 protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
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Applications:
Immunohistochemistry, Western Blot

Clone:
4-1-18

Conjugate:
Unconjugated

Gene:
CASP3

Gene Alias:
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
836

Content And Storage:
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Form:
Liquid

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Immunogen:
__

Quantity:
10 mg

Primary or Secondary:
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Target Species:
__

Product Type:
__

Isotype:
__

Applications:
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Clone:
__

Conjugate:
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Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Protect from light

Form:
Solid

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Antigen:
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Classification:
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Concentration:
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Formulation:
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Gene Accession No.:
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Gene Symbols:
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Quantity:
500 μg

Primary or Secondary:
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Target Species:
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Product Type:
__

Isotype:
__

Applications:
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Clone:
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Conjugate:
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Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

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__

Content And Storage:
__

Form:
__