35-889-880
Granzyme B Monoclonal Antibody (NGZB), PE-Cyanine5.5, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 35-889-880-Each-of-1 | In Stock | ₹ 14,202.96 |
35-889-880 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,202.96
GST (18%): ₹ 2,556.533
Total Price: ₹ 16,759.493
Antigen
Granzyme B
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P04187
Gene Symbols
GZMB
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14939
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
NGZB
Conjugate
PE-Cyanine5.5
Gene
GZMB
Gene Alias
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells
- Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells
- Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells
- The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Granzyme B during cytotoxic T cell-induced apoptosis
- Granzyme B enters target cells to cleave caspase-3 and initiate the caspase cascade leading to DNA fragmentation and apoptosis
- Granzyme B can also act through a mitochondrial apoptosis pathway by cleaving the Bid protein
- Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells
- A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified.
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Antigen: Granzyme B
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P04187
Gene Symbols: GZMB
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14939
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: NGZB
Conjugate: PE-Cyanine5.5
Gene: GZMB
Gene Alias: AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Granzyme B
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P04187
Gene Symbols:
GZMB
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14939
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
NGZB
Conjugate:
PE-Cyanine5.5
Gene:
GZMB
Gene Alias:
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Granzyme B
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P04187
Gene Symbols: GZMB
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14939
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: NGZB
Conjugate: PE-Cyanine5.5
Gene: GZMB
Gene Alias: AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Granzyme B
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P04187
Gene Symbols:
GZMB
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14939
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
NGZB
Conjugate:
PE-Cyanine5.5
Gene:
GZMB
Gene Alias:
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Connexin 32
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: P08033, P28230
Gene Symbols: GJB1
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14618, 29584
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Frozen), Western Blot
Clone: 5F9A9
Conjugate: Unconjugated
Gene: GJB1
Gene Alias: CMTX; CMTX1; Cnx32; connexin 32; connexin-32; CX32; Cxn-32; GAP junction 28 kDa liver protein; gap junction beta-1 protein; gap junction membrane channel protein beta 1; gap junction protein beta 1; gap junction protein, beta 1; gap junction protein, beta 1, 32kDa; Gjb1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Antigen:
Connexin 32
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
P08033, P28230
Gene Symbols:
GJB1
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14618, 29584
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Western Blot
Clone:
5F9A9
Conjugate:
Unconjugated
Gene:
GJB1
Gene Alias:
CMTX; CMTX1; Cnx32; connexin 32; connexin-32; CX32; Cxn-32; GAP junction 28 kDa liver protein; gap junction beta-1 protein; gap junction membrane channel protein beta 1; gap junction protein beta 1; gap junction protein, beta 1; gap junction protein, beta 1, 32kDa; Gjb1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Antigen: SAP97
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: Q12959, Q62696, Q811D0
Gene Symbols: DLG1
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 13383, 1739, 25252
Content And Storage: -20°C
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 2D11
Conjugate: Unconjugated
Gene: DLG1
Gene Alias: B130052P05Rik; discs large homolog 1; discs large homolog 1, scribble cell polarity complex component; discs large MAGUK scaffold protein 1; discs, large homolog 1; discs, large homolog 1 (Drosophila); discs, large homolog 1 (Drosophila) transcript variant 6-v1; discs, large homolog 1 (Drosophila) transcript variant 6-v2; disks large homolog 1; dJ1061C18.1.1; DKFZp761P0818; DKFZp781B0426; DLG1; Dlgh1; Drosophila discs-large tumor suppressor homologue (synapse associated protein); E-dlg/SAP97; Embryo-dlg/synapse-associated protein 97; hDlg; mKIAA4187; presynaptic protein SAP97; SAP97; SAP-97; synapse-associated protein 97
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
SAP97
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
Q12959, Q62696, Q811D0
Gene Symbols:
DLG1
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
13383, 1739, 25252
Content And Storage:
-20°C
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
2D11
Conjugate:
Unconjugated
Gene:
DLG1
Gene Alias:
B130052P05Rik; discs large homolog 1; discs large homolog 1, scribble cell polarity complex component; discs large MAGUK scaffold protein 1; discs, large homolog 1; discs, large homolog 1 (Drosophila); discs, large homolog 1 (Drosophila) transcript variant 6-v1; discs, large homolog 1 (Drosophila) transcript variant 6-v2; disks large homolog 1; dJ1061C18.1.1; DKFZp761P0818; DKFZp781B0426; DLG1; Dlgh1; Drosophila discs-large tumor suppressor homologue (synapse associated protein); E-dlg/SAP97; Embryo-dlg/synapse-associated protein 97; hDlg; mKIAA4187; presynaptic protein SAP97; SAP97; SAP-97; synapse-associated protein 97
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ