36-480-0

Claudin 4 Polyclonal Antibody (ZMD.306), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 36-480-0-Each-of-1 In Stock ₹ 38,502.00

36-480-0 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

Claudin 4

Classification

Polyclonal

Concentration

0.25 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

O35054

Gene Symbols

Cldn4

Immunogen

Synthetic peptide derived from the C-terminal region of mouse Claudin-4

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

ZMD.306

Conjugate

Unconjugated

Gene

Cldn4

Gene Alias

Cep-r; claudin 4; CLAUDIN4; claudin-4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPER; CPE-R; CPE-receptor; Cpetr; CPETR1; h CPE-receptor; hCPE-R; WBSCR8; Williams-Beuren syndrome chromosomal region 8 protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12740, 304407

Content And Storage

-20°C

Form

Liquid

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Description

  • Reactivity has been confirmed with mouse and rat kidney homogenates
  • On western blots a 22 kDa band is observed and a 44 kDa band representing dimerized protein may be observed
  • Claudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions
  • Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux
  • Claudin-4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life
  • The overexpression of Claudin-4 has been shown to decrease paracellular electrical conductance due to a selective decrease in Na+ permeability, with no significant decrease in Cl<sup>-</sup> permeability
  • In ovarian carcinoma cells, Claudin-3 and Claudin-4 exhibit upregulation at both mRNA and protein levels
  • Claudin-4 is also overexpressed in pancreatic cancer tissues and cell lines, and in other epithelial cancers
  • The Claudin-4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Compare Similar Items

Show Difference

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Invitrogen

36-480-0

--


Antigen:
Claudin 4

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
O35054

Gene Symbols:
Cldn4

Immunogen:
Synthetic peptide derived from the C-terminal region of mouse Claudin-4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
ZMD.306

Conjugate:
Unconjugated

Gene:
Cldn4

Gene Alias:
Cep-r; claudin 4; CLAUDIN4; claudin-4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPER; CPE-R; CPE-receptor; Cpetr; CPETR1; h CPE-receptor; hCPE-R; WBSCR8; Williams-Beuren syndrome chromosomal region 8 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12740, 304407

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

36-490-0

--


Antigen:
Connexin 40

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P28234, P36382, Q01231

Gene Symbols:
Gja5

Immunogen:
Synthetic peptide derived from the C-terminal region of the mouse and rat Connexin 40 (Cx40) proteins. The human sequence at this location differs by only one amino acid.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
Gja5

Gene Alias:
5730555N10Rik; ATFB11; Cnx40; connexin 40; connexin-40; Cx40; Cxn-40; Gap junction alpha-5 protein; gap junction membrane channel protein alpha 5; gap junction protein; gap junction protein alpha 5; gap junction protein alpha 5 40kDa; gap junction protein, alpha 5; GJA5; Gja-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14613, 2702, 50563

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

36-492-5

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
25 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Img

Fischer Scientific

36-495

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
5 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__