37-616-3182

CD163 Monoclonal Antibody (TNKUPJ), Brilliant Ultra Violet™ 661, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 37-616-3182-Each-of-1 In Stock ₹ 33,796.20

37-616-3182 - Each of 1

₹ 33,796.20

In Stock

Quantity

1

Base Price: ₹ 33,796.20

GST (18%): ₹ 6,083.316

Total Price: ₹ 39,879.516

Antigen

CD163

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q2VLH6

Gene Symbols

CD163

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

93671

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

TNKUPJ

Conjugate

Brilliant Ultraviolet 661

Gene

CD163

Gene Alias

CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

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Description

  • CD163 (M130 antigen, Ber-Mac3, Ki-M8, SM4) is a 130 kDa membrane glycoprotein, a member of the scavenger receptor cysteine-rich superfamily, and a receptor for the hemoglobin-haptoglobin complex
  • CD163 protects tissues from free hemoglobin-mediated oxidative damage, and may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme
  • CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation
  • Specifically, CD163 is present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal centers of lymphoid follicles, interdigitating reticulum cells and Langerhan's cells
  • CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes
  • CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone
  • Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant
  • CD163 binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner, and exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP1S phenotype
  • Further, CD163 also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

Compare Similar Items

Show Difference

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Fischer Scientific

37-616-3182

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Antigen:
CD163

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q2VLH6

Gene Symbols:
CD163

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
93671

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
TNKUPJ

Conjugate:
Brilliant Ultraviolet 661

Gene:
CD163

Gene Alias:
CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

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Invitrogen

37-620-0

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Antigen:
DDB1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q16531, Q3U1J4

Gene Symbols:
DDB1

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13194, 1642

Content And Storage:
-20°C

Isotype:
IgG1 κ

Applications:
ELISA, Immunoprecipitation, Western Blot

Clone:
2B12D1

Conjugate:
Unconjugated

Gene:
DDB1

Gene Alias:
127kDa; AA408517; damage specific DNA binding protein 1; damaged-DNA recognition protein 1; damage-specific DNA binding protein 1, 127kDa; damage-specific DNA-binding protein 1; damage-specific DNA-binding protein, DNA repair; DDB p127 subunit; DDB1; DDBa; DNA damage-binding protein 1; DNA damage-binding protein a; DNA repair protein; HBV X-associated protein 1; p127-Ddb1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; UV-DDB1; XAP1; XAP-1; xeroderma pigmento; Xeroderma pigmentosum group E-complementing protein; XPCE; XPE; XPE-BF; XPE-binding factor

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

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37-627-9941

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Antigen:
CD279 (PD-1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q15116

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100135775, 5133

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
eBioJ105 (J105)

Conjugate:
Brilliant Ultraviolet 661

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human, Rhesus Monkey

Form:
Liquid

Img

Fischer Scientific

37-627-9942

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Antigen:
CD279 (PD-1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q15116

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100135775, 5133

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
eBioJ105 (J105)

Conjugate:
Brilliant Ultraviolet 661

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Rhesus Monkey

Form:
Liquid