3844443
NKp46 Mouse anti-Human, Unlabeled, Clone: 9E2/NKP46, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
NKp46
Applications
Flow Cytometry
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Purification Method
Affinity Purified
Clone
9E2/NKP46
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Immunogen
Human NKp46 Recombinant Protein
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- NKp46, a major cytoxicity receptor of NK cells, is a type I membrane glycoprotein (46kDaa) is expressed on resting and activated NK cells
- Its extracellular region contains two C2-type, Ig-like domains
- The transmembrane domain contains a positively charged amino acid (Arg) which could be involved in stabilizing the association with CD3ζ
- Its intracellular region does not contain immunoreceptor tyrosine-based activating motifs (ITAM), but it is linked to intracytoplasmic transduction machinery by its association with CD3ζ and FcεRIγ adaptor proteins
- NKp46 along with NKp30 and NKp44 are referred to as natural cytoxicity receptors (NCR) and play a very important role in killing virus-infected, tumor cells and MHC-class I-unprotected cells
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: 9E2 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry
Compare Similar Items
Show Difference
Antigen: NKp46
Applications: Flow Cytometry
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: 9E2/NKP46
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Immunology
Immunogen: Human NKp46 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
NKp46
Applications:
Flow Cytometry
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
9E2/NKP46
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Immunology
Immunogen:
Human NKp46 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Target Species: __
Isotype: __
Purification Method: __
Clone: __
Classification: __
Host Species: __
Research Discipline: __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Target Species:
__
Isotype:
__
Purification Method:
__
Clone:
__
Classification:
__
Host Species:
__
Research Discipline:
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
__
Antigen: CD194
Applications: Flow Cytometry
Conjugate: PE-Cyanine7
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: 1G1
Classification: Monoclonal
Host Species: Mouse
Research Discipline: __
Immunogen: Human CCR4 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD194
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine7
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
1G1
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
__
Immunogen:
Human CCR4 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD19
Applications: Flow Cytometry
Conjugate: Alexa Fluor 700
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: HIB19
Classification: Monoclonal
Host Species: Mouse
Research Discipline: __
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD19
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 700
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
HIB19
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
__
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.