3851789

PKA[C] Mouse, Unlabeled, Clone: 5B, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PKA[C]

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG2b

Purification Method

Affinity Purified

Clone

5B

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Human, Mouse, Rat

Immunogen

Human PKA[Cα] subunit aa. 18-347

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

Description

  • cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic (C) and regulatory (R)
  • Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ
  • These subunits define type I and II cAMP-dependent protein kinases
  • Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active
  • Type I and type II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ)
  • Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity
  • The levels of expression of the different subunits vary according to cell and tissue type
  • Immunofluorescence, Western Blotting

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3851789

Mouse Monoclonal Antibody...


Antigen:
PKA[C]

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2b

Purification Method:
Affinity Purified

Clone:
5B

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Human PKA[Cα] subunit aa. 18-347

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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250μg/mL

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Research Discipline:
Cell Biology

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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
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Purification Method:
Affinity Purified

Clone:
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Western Blot

Conjugate:
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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

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RUO

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Human PARP aa. 22-219

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Store undiluted at -20°C.

Img

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3851879

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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

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Purification Method:
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Clone:
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