3853642
IL-17A Rat anti-Mouse, Unlabeled, Clone: TC11-18H10, BD
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL-17A
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Rat
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Clone
TC11-18H10
Applications
Blocking Assay, ELISA, Flow Cytometry
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Mouse
Immunogen
Recombinant Mouse IL-17 Protein
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Description
- The TC11-18H10 antibody reacts with recombinant and natural mouse IL-17A proteins
- IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses
- Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells
- It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo
- The TC11-18H10 antibody has been reported to neutralize IL-17A activity
- Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways
- The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8-thymocytes
- Blocking Assay, ELISA, Intracellular Staining, Western Blotting
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Antigen: IL-17A
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: TC11-18H10
Applications: Blocking Assay, ELISA, Flow Cytometry
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Recombinant Mouse IL-17 Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
IL-17A
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
TC11-18H10
Applications:
Blocking Assay, ELISA, Flow Cytometry
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Recombinant Mouse IL-17 Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
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