3855561
5-Lipoxygenase Mouse, Unlabeled, Clone: 33, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
5-Lipoxygenase
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG1
Purification Method
Affinity Purified
Clone
33
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Chicken, Human, Mouse, Rat
Immunogen
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Description
- 5-Lipoxygenase (5-LO) is the initial enzyme that converts arachidonic acid to leukotrienes, which are important inflammatory and vasoconstrictive metabolites
- It is activated in response to a number of stimuli, such as differentiation and allergen challenges
- The 5-LO gene, abundantly expressed in placenta, lung, and leukocytes, encodes a protein of 674 amino acids with an apparent molecular weight of 78kDa
- 5-LO is a Ca 2 + and ATP-dependent enzyme that translocates from the cytosol to either a nuclear or plasma membrane compartment following activation
- A proline-rich domain of 5-LO (amino acids 566-577) has been identified as a binding site for the PTyr-binding protein, Grb2
- This Grb2 site links tyrosine kinases with activation and redistribution of 5-LO
- Furthermore, tyrosine kinase inhibitors increase the activity of 5-LO and block the enzyme's subcellular redistribution
- Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Compare Similar Items
Show Difference
Antigen: 5-Lipoxygenase
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 33
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Chicken, Human, Mouse, Rat
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
5-Lipoxygenase
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
33
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Chicken, Human, Mouse, Rat
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: BM28
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 46
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Chicken, Human, Mouse, Rat
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
BM28
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
46
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Human, Mouse, Rat
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: __
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Classification: __
Host Species: __
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Formulation: __
Isotype: __
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Applications: __
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Primary or Secondary: __
Content And Storage: __
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Formulation:
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Conjugate:
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Antigen: Eps8
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 15
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Human, Mouse, Rat
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Eps8
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
15
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Human, Mouse, Rat
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.