3855966

Hsp90 Mouse, Unlabeled, Clone: 68, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Hsp90

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Description

Heat Shock Protein-90

Clone

68

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Chicken, Human, Mouse, Rat

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

Description

  • The 90kDa heat shock protein (Hsp90), a highly conserved stress-induced protein, is abundantly expressed in most tissues under nonstress conditions and is required for eukaryotic cell viability
  • Hsp90 interacts with a number of signaling molecules, other heat shock proteins, and cytoskeletal proteins
  • However, the function of Hsp90 in these complexes remains unclear
  • It is thought that Hsp90 plays a common role in a number of diverse signaling systems due to its physical association with v-Src family tyrosine kinases, steroid hormone receptors, the Raf serine/threonine kinase, the basic-helix-loop-helix dioxin receptor, and the βγ subunits of G proteins
  • Immunofluorescence, Immunoprecipitation, Western Blotting

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Antigen:
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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

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Clone:
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