3967375

DLP1 Mouse, Unlabeled, Clone: 8, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

DLP1

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Description

Dynamin Like Protein-1; DVLP

Clone

8

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Human, Mouse, Rat

Immunogen

Rat DLP1 aa. 601-722

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

Description

  • Dynamins, phosphoproteins with intrinsic GTPase activities, play an important role during early endocytosis
  • The GTPase activity is stimulated in vitro by microtubules, SH3 domain containing-proteins, and Protein Kinase (PKC)- mediated phosphorylation
  • Although highly related, dynamins are differentially expressed in an organism
  • For instance, dynamin I is found only in the nervous system, dynamin II is ubiquitously expressed, and dynamin III is located in lung, testis and brain
  • Due to four alternative splicing products for each of the dynamins, the dynamin family contains at least 12 different members
  • The Dynamin Like Protein-1 (DLP1) is a new member of the dynamin family of proteins
  • DLP1 (also known as DVLP) is widely expressed as two alternatively spliced products, each with different tissue expression patterns
  • The larger product is about 84kDa and reportedly found only in the brain, whereas the 79kDa product is ubiquitously expressed
  • Unlike dynamins I-III which co-localize with endocytotic vesicles, DLP1 is found aligned with microtubules and with the endoplasmic reticulum, suggesting a secretory function for this novel protein
  • Host Species: Mouse Clone: 8 Isotype: IgG1 Species Reactivity: Rat Immunogen: Rat DLP1 aa
  • 601-722 Formula Weight [Chemical]: 79-84kDa Immunofluorescence, Western Blotting

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Mouse Monoclonal Antibody...


Antigen:
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Concentration:
250μg/mL

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Host Species:
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Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
Dynamin Like Protein-1; DVLP

Clone:
8

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
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Content And Storage:
Store undiluted at -20°C.

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