3967715
Oct3/4 Mouse, Unlabeled, Clone: 40/OCT-3, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
OCT3/4
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
Oct3, OTF3, Oct4, OTF4, POU5F1
Clone
40/OCT-3
Applications
In vitro Assay, Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human, Mouse
Immunogen
Mouse Oct3 aa. 252-372 Recombinant Protein
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Description
- Development of a multicellular organism from a single fertilized cell is regulated by the coordinated activity of DNA transcription factors
- Oct3/4, a member of the POU family of transcription factors, functions in pluripotent cells of early embryonic stem cell (ES) lines and embryonal carcinomas (EC)
- Other members of the POU family include Oct1, Oct2, Pit-1, and unc-86
- The POU domain, a 150-amino acid region that determines binding specificity, is conserved among these proteins and consists of 3 subdomains: POU-specific A and B subdomains and a homeobox-like subdomain
- Oct3/4 is expressed in undifferentiated cells, but is lost as cells are induced to differentiate
- Oct3/4 is not expressed in adult tissues
- The interaction of Oct3/4 with SOX2, another embryonic transcription factor, produces an active complex that regulates expression of genes such as Nanog, UTF1, and FGF4
- Although Oct3/4 is specifically phosphorylated on serine residues, this modification is not required for DNA binding, but may affect its transactivation potential
- Thus, Oct3/4 is a transcription factor that plays an important role in determining early steps of embryogenesis and differentiation
- Host Species: Mouse Clone: 40 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Mouse Oct3 aa
- 252-372 Recombinant Protein Formula Weight [Chemical]: 46kDa Western Blotting
Compare Similar Items
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Antigen: OCT3/4
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: Oct3, OTF3, Oct4, OTF4, POU5F1
Clone: 40/OCT-3
Applications: In vitro Assay, Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse
Immunogen: Mouse Oct3 aa. 252-372 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
OCT3/4
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
Oct3, OTF3, Oct4, OTF4, POU5F1
Clone:
40/OCT-3
Applications:
In vitro Assay, Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse
Immunogen:
Mouse Oct3 aa. 252-372 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: __
Concentration: __
Classification: __
Host Species: Mouse
Research Discipline: __
Formulation: __
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: __
Clone: MOPC-21
Applications: Flow Cytometry, Western Blot
Conjugate: R-PE
Regulatory Status: __
Target Species: Non-human Primate
Immunogen: __
Primary or Secondary: __
Content And Storage: Undiluted at 4°C
Antigen:
__
Concentration:
__
Classification:
__
Host Species:
Mouse
Research Discipline:
__
Formulation:
__
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
__
Clone:
MOPC-21
Applications:
Flow Cytometry, Western Blot
Conjugate:
R-PE
Regulatory Status:
__
Target Species:
Non-human Primate
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
Undiluted at 4°C
Antigen: __
Concentration: __
Classification: __
Host Species: __
Research Discipline: __
Formulation: __
Isotype: __
Purification Method: __
Description: __
Clone: __
Applications: __
Conjugate: __
Regulatory Status: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Concentration:
__
Classification:
__
Host Species:
__
Research Discipline:
__
Formulation:
__
Isotype:
__
Purification Method:
__
Description:
__
Clone:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Target Species:
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
__
Antigen: CD117
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: __
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgG2b κ
Purification Method: Affinity Purified
Description: c-KIT; W; SCFR; Stem Cell Factor Receptor; Sl; Steel Factor Receptor; Ssm
Clone: 2B8
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Mouse Bone Marrow Mast Cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD117
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
__
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgG2b κ
Purification Method:
Affinity Purified
Description:
c-KIT; W; SCFR; Stem Cell Factor Receptor; Sl; Steel Factor Receptor; Ssm
Clone:
2B8
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Mouse Bone Marrow Mast Cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.