3968807

CD138 Mouse anti-Human, FITC, Clone: MI15, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD138

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

Syndecan; SDC; Syndecan 1; SDC1; SYND1

Clone

MI15

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human U266 and XG-1 Myeloma Cell Lines

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • Reacts with CD138 (Syndecan-1), an 85-92kDa single chain transmembrane protein, strongly expressed on multiple-myeloma-derived cell lines and malignant plasma cell populations
  • It is also expressed on pre-B cells, immature B cells, and plasma cells, but not on mature circulating B-lymphocytes
  • Syndecan-1 is a member of the family of transmemrane heparan sulfate proteoglycans
  • It is also expressed on some non-hematopoietic cells, including embryonic mesenchymal cells, vascular smooth muscle cells, endothelial and neural cells
  • CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III, and V, tenascin, thrombospondin, and antithrombin III
  • It is considered an extracellular matrix receptor that may serve as a co-receptor for fibroblast growth factor and related molecules
  • Monoclonal antibody MI15 blocks the binding of clone B-B4 but not clone DL-101 (other anti-syndecan-1 antibodies) by flow cytometric analysis
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Mouse Clone: MI15 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry

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Antigen:
CD138

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Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
Syndecan; SDC; Syndecan 1; SDC1; SYND1

Clone:
MI15

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human U266 and XG-1 Myeloma Cell Lines

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Isotype:
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Purification Method:
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Clone:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Primary or Secondary:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.