3971037
IL-17A Mouse anti-Human, Alexa Fluor 647, Clone: SCPL1362, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL-17A
Applications
Flow Cytometry
Conjugate
Alexa Fluor 647
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
IL-17; IL-17A; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Clone
SCPL1362
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- Human IL-17A, also known as IL-17, is a proinflammatory cytokine that is encoded by the IL17A gene in chromosome 6
- IL-17A is produced as a disulfide-linked homodimer comprised of two mature 136-amino acid polypeptides
- It is a member of the IL-17 family of structurally related cytokines, designated IL-17A through IL-17F
- Activated memory T cells, especially Th17 cells (specialized IL-17A-producing CD4+ T cells distinct from Th1 and Th2 cells) produce IL-17 and provide protective immunity against pathogens
- Activated CD8+ T cells, γδT cells, NK cells and neutrophils can also be activated to produce IL-17A
- IL-17A binds to and exerts its biological activity through IL-17 receptors (IL-17R) that are expressed by a variety of target cells including fibroblasts, epithelial and endothelial cells, monocytes/macrophages and mast cells
- The ubiquitous IL-17R expression pattern may explain the broad tissue responsiveness to IL-17
- IL-17 induces stromal cells to secrete cytokines and chemokines involved in inflammatory and hematopoietic processes
- For example, IL-17 induces fibroblasts to produce IL-6, IL-8, G-CSF and express increased surface ICAM-1
- The SCPL1362 antibody reacts with human IL-17A
- Host Species: Mouse Clone: O33-782 Isotype: IgG1, κ Species Reactivity: Human Flow Cytometry, Intracellular Staining
Compare Similar Items
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Antigen: IL-17A
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: IL-17; IL-17A; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Clone: SCPL1362
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
IL-17A
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
IL-17; IL-17A; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Clone:
SCPL1362
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Cdk1
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Isotype: IgG1
Purification Method: Affinity Purified
Description: Cdc2, p34
Clone: 1
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Cdk1
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
Cdc2, p34
Clone:
1
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: IL-17A
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: __
Clone: TC11-18H10
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
IL-17A
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
__
Clone:
TC11-18H10
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Itch
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse, Rabbit, Rat
Isotype: IgG1
Purification Method: Affinity Purified
Description: __
Clone: 32
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Itch
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rabbit, Rat
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
__
Clone:
32
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.