40-080-0

Phospho-SMAD2 (Ser465, Ser467) Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 40-080-0-Each-of-1 In Stock ₹ 42,780.00

40-080-0 - Each of 1

₹ 42,780.00

In Stock

Quantity

1

Base Price: ₹ 42,780.00

GST (18%): ₹ 7,700.40

Total Price: ₹ 50,480.40

Antigen

Phospho-SMAD2 (Ser465, Ser467)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMAD2

Gene Alias

7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4087

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

Q15796

Gene Symbols

SMAD2

Immunogen

Synthetic peptide encompassing the phosphorylated serine 465 and 467 residues of human, mouse, and rat Smad2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Invitrogen

44-244-G

--

Img

Invitrogen

39-570-0

--

Img

Invitrogen

38-540-0

--

Img

Invitrogen

44-246-G

--

Img

Invitrogen

44-126-0G

--

Img

Invitrogen

40-640-0

--

Img

Invitrogen

44-612-G

--

Img

Invitrogen

36-920-0

--

Description

  • SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
  • SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
  • Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
  • In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
  • The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
  • The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
  • SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
  • Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.

Compare Similar Items

Show Difference

Img

Invitrogen

40-080-0

--


Antigen:
Phospho-SMAD2 (Ser465, Ser467)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4087

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q15796

Gene Symbols:
SMAD2

Immunogen:
Synthetic peptide encompassing the phosphorylated serine 465 and 467 residues of human, mouse, and rat Smad2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Applied Biosystems™

40-085-4

--


Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
450 mL

Primary or Secondary:
__

Target Species:
__

Product Type:
Ethyl Acetate

Isotype:
__

Img

Invitrogen

40-090-0

--


Antigen:
Connexin 30.3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GJB4

Gene Alias:
Cnx30.3; connexin 30.3; connexin-30.3; CX30.3; Cxn-30.3; EKV; gap junction beta-4 protein; gap junction membrane channel protein beta 4; gap junction protein beta 4; gap junction protein, beta 4; gap junction protein, beta 4, 30.3kDa; Gjb4; Gjb-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14621

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q02738

Gene Symbols:
GJB4

Immunogen:
Synthetic peptide derived from the internal region of the mouse connexin 30.3 protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

LIFE TECHNOLOGIES

40-098-1

--


Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
6-Tamra NHS/DMSO

Isotype:
__