40-600-8180

CD8a Monoclonal Antibody (53-6.7), Brilliant Violet™ 605, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 40-600-8180-Each-of-1 In Stock ₹ 14,973.00

40-600-8180 - Each of 1

₹ 14,973.00

In Stock

Quantity

1

Base Price: ₹ 14,973.00

GST (18%): ₹ 2,695.14

Total Price: ₹ 17,668.14

Antigen

CD8a

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.

P01731, P10300

Gene Symbols

Cd8a, Cd8b1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12525, 12526

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

53-6.7

Conjugate

Brilliant Violet 605

Gene

Cd8a

Gene Alias

BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

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Description

  • Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
  • CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
  • CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
  • CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
  • Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
  • Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
  • Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.

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Img

Fischer Scientific

40-600-8180

--


Antigen:
CD8a

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P01731, P10300

Gene Symbols:
Cd8a, Cd8b1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12525, 12526

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
53-6.7

Conjugate:
Brilliant Violet 605

Gene:
Cd8a

Gene Alias:
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Fischer Scientific

40-600-8182

--


Antigen:
CD8a

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P01731, P10300

Gene Symbols:
Cd8a, Cd8b1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12525, 12526

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
53-6.7

Conjugate:
Brilliant Violet 605

Gene:
Cd8a

Gene Alias:
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Fischer Scientific

40-600-8841

--


Antigen:
CD8a

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P01732, P10966

Gene Symbols:
Cd8a, CD8B

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
925, 926

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
RPA-T8

Conjugate:
Brilliant Violet 605

Gene:
CD8B

Gene Alias:
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Fischer Scientific

40-600-8842

--


Antigen:
CD8a

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P01732, P10966

Gene Symbols:
Cd8a, CD8B

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
925, 926

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
RPA-T8

Conjugate:
Brilliant Violet 605

Gene:
CD8B

Gene Alias:
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid