40-602-7942

CD27 Monoclonal Antibody (O323), Brilliant Violet™ 605, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 40-602-7942-Each-of-1 In Stock ₹ 30,716.04

40-602-7942 - Each of 1

₹ 30,716.04

In Stock

Quantity

1

Base Price: ₹ 30,716.04

GST (18%): ₹ 5,528.887

Total Price: ₹ 36,244.927

Antigen

CD27

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.

P26842

Gene Symbols

CD27

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

939

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

O323

Conjugate

Brilliant Violet 605

Gene

CD27

Gene Alias

CD antigen 27, CD27, CD27 antigen, CD27 molecule, CD27L receptor, LPFS2, S152, S152. LPFS2, sCD27, soluble CD27, T cell activation antigen S152, T14, T-cell activation antigen CD27, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30
  • The TNF superfamily members are known for the regulation of cell proliferation and death
  • In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes
  • High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors
  • CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals
  • CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells
  • Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid
  • Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies
  • RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70
  • CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
  • Diseases associated with CD27 dysfunction include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.

Compare Similar Items

Show Difference

Img

Fischer Scientific

40-602-7942

--


Antigen:
CD27

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P26842

Gene Symbols:
CD27

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
939

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
O323

Conjugate:
Brilliant Violet 605

Gene:
CD27

Gene Alias:
CD antigen 27, CD27, CD27 antigen, CD27 molecule, CD27L receptor, LPFS2, S152, S152. LPFS2, sCD27, soluble CD27, T cell activation antigen S152, T14, T-cell activation antigen CD27, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Fischer Scientific

40-603-3841

--


Antigen:
CD33

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P20138

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
945

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
WM-53 (WM53)

Conjugate:
Brilliant Violet 605

Gene:
CD33

Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Fischer Scientific

40-603-3842

--


Antigen:
CD33

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P20138

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
945

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
WM-53 (WM53)

Conjugate:
Brilliant Violet 605

Gene:
CD33

Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Fischer Scientific

40-603-8180

--


Antigen:
CD38

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P56528

Gene Symbols:
CD38

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12494

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
90

Conjugate:
Brilliant Violet 605

Gene:
CD38

Gene Alias:
2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADPRC 1, ADPRC1, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, Cd38, CD38 antigen, CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase), CD38 antigen (p45), CD38 antigen p45, CD38 molecule, CD38H, Cd38-rs1, cluster of differentiation 38, cyclic ADP-ribose hydrolase 1, ecto-nicotinamide adenine dinucleotide glycohydrolase, I-19, NAD(+) nucleosidase, NAD+ nucleosidase, NIM-R5 antigen, T10

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid