41-473-1180

IFN gamma Monoclonal Antibody (XMG1.2), Brilliant Violet™ 480, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 41-473-1180-Each-of-1 In Stock ₹ 12,834.00

41-473-1180 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

IFN gamma

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P01580

Gene Symbols

IFNG

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15978

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

XMG1.2

Conjugate

Brilliant Violet 480

Gene

IFNG

Gene Alias

BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Related Products

Img

Fischer Scientific

416-7311-80

--

Img

Fischer Scientific

41-473-1182

--

Img

Fischer Scientific

407-7311-80

--

Img

Fischer Scientific

416-7311-82

--

Img

Fischer Scientific

407-7311-82

--

Img

Fischer Scientific

50-100-30

--

Img

Fischer Scientific

40-673-1180

--

Img

Fischer Scientific

40-673-1182

--

Description

  • The XMG1.2 antibody reacts with mouse interferon (IFN) gamma
  • The XMG1.2 antibody is a neutralizing antibody
  • Mouse IFN gamma is a 20 kDa factor produced by activated T, B and NK cells, and is an anti-viral and anti-parasitic cytokine
  • IFN gamma, in synergy with other cytokines such as TNF alpha, inhibits proliferation of normal and transformed cells
  • Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN gamma
  • Glycosylation of IFN gamma does not affect its biological activity
  • Applications Reported: This XMG1.2 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This XMG1.2 antibody has been tested by intracellular staining followed by flow cytometric analysis of stimulated mouse splenocytes using the Intracellular Fixation & Permeabilization Buffer Set (88-8824-00) and protocol
  • BV 480 is a dye that emits at 479nm and is intended for use on cytometers equipped with a violet (405nm) laser
  • Excitation: 440nm; Emission: 479nm; Laser: Violet Laser
  • BV is a trademark or registered trademark of Becton, Dickinson and Company or its affiliates, and is used under license
  • Powered by Sirigen
  • IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines
  • IFN gamma is a dimeric protein consisting of two 146 amino acid subunits
  • IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa
  • On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation
  • The biological activity of the IFN gamma homodimer is highly species specific
  • Human IFN gamma does not show cross-reactivity with mouse
  • IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes
  • IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines
  • Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway
  • IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma
  • IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN
  • IFN gamma gene mutations are associated with aplastic anemia.

Compare Similar Items

Show Difference

Img

Fischer Scientific

41-473-1180

--


Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01580

Gene Symbols:
IFNG

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15978

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
XMG1.2

Conjugate:
Brilliant Violet 480

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

41-473-1182

--


Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01580

Gene Symbols:
IFNG

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15978

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
XMG1.2

Conjugate:
Brilliant Violet 480

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

41-473-282

--


Antigen:
Mouse IgG2b kappa

Classification:
__

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Control, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
eBMG2b

Conjugate:
eFluor 570

Gene:
__

Gene Alias:
IgG2; Immunoglobulin G; Immunoglobulin G2; ImmunoglobulinG; ImmunoglobulinG2

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Isotype Control (Primary)

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG2b κ

Img

Invitrogen

41-480-0

--


Antigen:
Cathepsin B

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P07858

Gene Symbols:
Ctsb

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1508

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4B11

Conjugate:
Unconjugated

Gene:
Ctsb

Gene Alias:
amyloid precursor protein secretase; APP secretase; APPS; cathepsin B; Cathepsin B heavy chain; Cathepsin B light chain; Cathepsin B1; CB; CPSB; Ctsb; cysteine protease; RSG-2

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1