41-604-5282

CD45R (B220) Monoclonal Antibody (RA3-6B2), Brilliant Violet™ 650, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 41-604-5282-Each-of-1 In Stock ₹ 30,117.12

41-604-5282 - Each of 1

₹ 30,117.12

In Stock

Quantity

1

Base Price: ₹ 30,117.12

GST (18%): ₹ 5,421.082

Total Price: ₹ 35,538.202

Antigen

CD45R (B220)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P06800, P08575

Gene Symbols

PTPRC

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19264, 5788

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

RA3-6B2

Conjugate

Brilliant Violet 650

Gene

PTPRC

Gene Alias

B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Related Products

Img

Fischer Scientific

41-604-5280

--

Img

Fischer Scientific

40-404-5282

--

Img

Fischer Scientific

40-704-5282

--

Img

Fischer Scientific

40-404-5280

--

Img

Fischer Scientific

40-704-5280

--

Img

Fischer Scientific

50-103-74

--

Img

Fischer Scientific

40-604-5282

--

Img

Fischer Scientific

41-404-5282

--

Description

  • CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family
  • PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
  • CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains
  • CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains
  • Further, these CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • In addition to its role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • Diseases associated with CD45 dysfunction include Severe Combined Immunodeficiency (T-cell negative, B-Cell Negative) and Hepatitis C.

Compare Similar Items

Show Difference

Img

Fischer Scientific

41-604-5282

--


Antigen:
CD45R (B220)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P06800, P08575

Gene Symbols:
PTPRC

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19264, 5788

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
RA3-6B2

Conjugate:
Brilliant Violet 650

Gene:
PTPRC

Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Fischer Scientific

41-604-5380

--


Antigen:
CD45.1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P06800

Gene Symbols:
Ptprc

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19264

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
A20

Conjugate:
Brilliant Violet 650

Gene:
Ptprc

Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, Leukocyte common antigen, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Fischer Scientific

41-604-5382

--


Antigen:
CD45.1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P06800

Gene Symbols:
Ptprc

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19264

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
A20

Conjugate:
Brilliant Violet 650

Gene:
Ptprc

Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, Leukocyte common antigen, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen

Host Species:
Mouse

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Fischer Scientific

41-604-5480

--


Antigen:
CD45.2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P06800

Gene Symbols:
Ptprc

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19264

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
104

Conjugate:
Brilliant Violet 650

Gene:
Ptprc

Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; LCA; L-CA; leukocyte common antigen; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase, receptor type, C; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid