4326082
c-Myc with control Mouse anti-Human, Unlabeled, Clone: 9E10., BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
c-Myc with control
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Isotype
IgG1
Purification Method
Affinity Purified
Clone
9E10.
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- The myc gene family contains at least seven closely related genes, c-myc, N-myc, L-myc, P-myc, R-myc, S-myc, and B-myc
- C-myc plays a role in proliferation, transformation, and differentiation
- It is expressed during embryonic development, in a wide variety of adult tissues, and is amplified in many tumors, particularly lung, breast, cervical and colon carcinomas
- Cellular localization has been described as nuclear and/or cytopasmic
- C-myc has three sequence motifs in the carboxy terminus, a leucine zipper, a helix-loop-helix, and a basic region
- It forms sequence-specific (CACGTG) DNA binding heterodimers with max, a helixloop-helix/leucine zipper protein
- Both the leucine zipper domain and the helixloop-helix motif of c-myc contribute to heterodimer formation
- DNA binding of myc-max dimers results in a conformational change of the DNA and transcriptional activation
- C-myc migrates at 62 kDa in SDS-PAGE
- Clone 9E10 recognizes human c-myc
- A synthetic peptide corresponding to a C-terminal epitope of the human c-myc protein (AEEQKLISEEDL) was used as an immunogen.
Compare Similar Items
Show Difference
Antigen: c-Myc with control
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 9E10.
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
c-Myc with control
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
9E10.
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: FoxP3
Applications: Flow Cytometry
Conjugate: Alexa Fluor 488
Regulatory Status: RUO
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 259D/C7
Classification: Monoclonal
Host Species: Mouse
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
FoxP3
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 488
Regulatory Status:
RUO
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
259D/C7
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Ig κ Light Chain
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: 187.1
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Ig κ Light Chain
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
187.1
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: IL-17F
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: O79-289
Classification: Monoclonal
Host Species: Mouse
Target Species: Mouse
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
IL-17F
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
O79-289
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Mouse
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.