44-802-A1
Phospho-IR/IGF1R (Tyr1158) Polyclonal Antibody, Alexa Fluor™ 488, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 44-802-A1-Each-of-1 | In Stock | ₹ 34,224.00 |
44-802-A1 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
Phospho-IR/IGF1R (Tyr1158)
Classification
Polyclonal
Formulation
Dulbecco's PBS with 0.2% BSA and 0.05% sodium azide, pH 7.3
Gene Accession No.
P06213, P08069
Gene Symbols
IGF1R, Insr
Immunogen
Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosine 1158 of the human insulin receptor (IR) (tyrosine 1131 for IGF1R)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunofluorescence
Conjugate
Alexa Fluor 488
Gene
IGF1R
Gene Alias
4932439J01Rik, A330103N21Rik, CD220, CD221, D630014A15Rik, D930020L01, HHF5, hyft, IGF1 Receptor, IGF-1 receptor, IGF1 Receptor beta, Igf1r, IGF-1R, IGF1R beta, IGF-I receptor, IGF-I Receptor beta, IGFIR, IGFIRC, IGFR, Igfr1, Insr, insulin like growth factor 1 receptor, insulin receptor, insulin receptor precursor, insulin receptor preproprotein, Insulin receptor subunit alpha, Insulin receptor subunit beta, Insulin-like growth factor 1 receptor, Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain, insulin-like growth factor 1 receptor beta subunit, insulin-like growth factor I receptor, insulin-like growth factor receptor 1, insulin-like growth factor receptor type 1, insulin-like growth factor-I receptor, insulin-like growth factor-I receptor precursor, IR, IR-A, IR-B, JTK13, line 186, soluble IGF1R variant 1, soluble IGF1R variant 2
Host Species
Rabbit
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3480, 3643
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- This antibody is predicted to react with mouse and rat
- Insulin and Insulin-like Growth Factor receptors are transmembrane tyrosine kinase receptors that play critical roles in development, cell growth and metabolism
- Insulin/Insulin-like growth factor-1 binding to the extracellular domain of IR and IGFR leads to autophosphorylation of the receptor and activation of the intrinsic tyrosine kinase activity, which allows appropriate substrates to be phosphorylated
- Phosphorylation sites that are unique to each receptor presumably play a key role in these signaling differences
- The catalytic loops within the tyrosine kinase domains contain a three tyrosine motif corresponding to Tyr1158, 1162 and 1163 (for the IR) and Tyr1131, 1135 and 1136 (for the IGF1R)
- Autophosphorylation of the tyrosine sites within the activation loop proceeds in a processive manner initiating at the second tyrosine (1162 or 1135), followed by phosphorylation at tyrosines 1158 (IGF-1R tyrosine 1131), 1163 (IGF-1R tyrosine 1136), resulting in the full activation of IR and IGF1R.
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Antigen: Phospho-IR/IGF1R (Tyr1158)
Classification: Polyclonal
Formulation: Dulbecco's PBS with 0.2% BSA and 0.05% sodium azide, pH 7.3
Gene Accession No.: P06213, P08069
Gene Symbols: IGF1R, Insr
Immunogen: Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosine 1158 of the human insulin receptor (IR) (tyrosine 1131 for IGF1R)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunofluorescence
Conjugate: Alexa Fluor 488
Gene: IGF1R
Gene Alias: 4932439J01Rik, A330103N21Rik, CD220, CD221, D630014A15Rik, D930020L01, HHF5, hyft, IGF1 Receptor, IGF-1 receptor, IGF1 Receptor beta, Igf1r, IGF-1R, IGF1R beta, IGF-I receptor, IGF-I Receptor beta, IGFIR, IGFIRC, IGFR, Igfr1, Insr, insulin like growth factor 1 receptor, insulin receptor, insulin receptor precursor, insulin receptor preproprotein, Insulin receptor subunit alpha, Insulin receptor subunit beta, Insulin-like growth factor 1 receptor, Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain, insulin-like growth factor 1 receptor beta subunit, insulin-like growth factor I receptor, insulin-like growth factor receptor 1, insulin-like growth factor receptor type 1, insulin-like growth factor-I receptor, insulin-like growth factor-I receptor precursor, IR, IR-A, IR-B, JTK13, line 186, soluble IGF1R variant 1, soluble IGF1R variant 2
Host Species: Rabbit
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3480, 3643
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-IR/IGF1R (Tyr1158)
Classification:
Polyclonal
Formulation:
Dulbecco's PBS with 0.2% BSA and 0.05% sodium azide, pH 7.3
Gene Accession No.:
P06213, P08069
Gene Symbols:
IGF1R, Insr
Immunogen:
Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosine 1158 of the human insulin receptor (IR) (tyrosine 1131 for IGF1R)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunofluorescence
Conjugate:
Alexa Fluor 488
Gene:
IGF1R
Gene Alias:
4932439J01Rik, A330103N21Rik, CD220, CD221, D630014A15Rik, D930020L01, HHF5, hyft, IGF1 Receptor, IGF-1 receptor, IGF1 Receptor beta, Igf1r, IGF-1R, IGF1R beta, IGF-I receptor, IGF-I Receptor beta, IGFIR, IGFIRC, IGFR, Igfr1, Insr, insulin like growth factor 1 receptor, insulin receptor, insulin receptor precursor, insulin receptor preproprotein, Insulin receptor subunit alpha, Insulin receptor subunit beta, Insulin-like growth factor 1 receptor, Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain, insulin-like growth factor 1 receptor beta subunit, insulin-like growth factor I receptor, insulin-like growth factor receptor 1, insulin-like growth factor receptor type 1, insulin-like growth factor-I receptor, insulin-like growth factor-I receptor precursor, IR, IR-A, IR-B, JTK13, line 186, soluble IGF1R variant 1, soluble IGF1R variant 2
Host Species:
Rabbit
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3480, 3643
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-IR/IGF1R (Tyr1158)
Classification: Polyclonal
Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.: P06213, P08069
Gene Symbols: IGF1R, Insr
Immunogen: Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosine 1158 of the human insulin receptor (IR) (tyrosine 1131 for IGF1R)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Gene: Insr
Gene Alias: 4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3480, 3643
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-IR/IGF1R (Tyr1158)
Classification:
Polyclonal
Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.:
P06213, P08069
Gene Symbols:
IGF1R, Insr
Immunogen:
Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosine 1158 of the human insulin receptor (IR) (tyrosine 1131 for IGF1R)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Gene:
Insr
Gene Alias:
4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3480, 3643
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-IR/IGF1R (Tyr1162, Tyr1163)
Classification: Polyclonal
Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.: P06213, P08069
Gene Symbols: IGF1R, Insr
Immunogen: Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosines 1162 and 1163 of the human insulin receptor (IR)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Gene: Insr
Gene Alias: 4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3480, 3643
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-IR/IGF1R (Tyr1162, Tyr1163)
Classification:
Polyclonal
Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.:
P06213, P08069
Gene Symbols:
IGF1R, Insr
Immunogen:
Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosines 1162 and 1163 of the human insulin receptor (IR)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Gene:
Insr
Gene Alias:
4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3480, 3643
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-IR/IGF1R (Tyr1158, Tyr1162, Tyr1163)
Classification: Polyclonal
Formulation: Dulbecco's PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3
Gene Accession No.: P06213, P08069, P15208, Q60751
Gene Symbols: IGF1R, Insr
Immunogen: Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosines 1158, 1162 and 1163 of the human insulin receptor (IR)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: Insr
Gene Alias: 4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16001, 16337, 3480, 3643
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-IR/IGF1R (Tyr1158, Tyr1162, Tyr1163)
Classification:
Polyclonal
Formulation:
Dulbecco's PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3
Gene Accession No.:
P06213, P08069, P15208, Q60751
Gene Symbols:
IGF1R, Insr
Immunogen:
Synthetic phosphopeptide derived from the region of IR/IGF1R that contains tyrosines 1158, 1162 and 1163 of the human insulin receptor (IR)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
Insr
Gene Alias:
4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16001, 16337, 3480, 3643
Content And Storage:
-20°C
Form:
Liquid