44-956

Phospho-PKC gamma (Thr514) Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 44-956-Each-of-1 In Stock ₹ 41,068.80

44-956 - Each of 1

₹ 41,068.80

In Stock

Quantity

1

Base Price: ₹ 41,068.80

GST (18%): ₹ 7,392.384

Total Price: ₹ 48,461.184

Antigen

Phospho-PKC gamma (Thr514)

Classification

Polyclonal

Formulation

Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.

P05129, P63318

Gene Symbols

PRKCG

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKC-gamma that contains threonine 514

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Gene

PRKCG

Gene Alias

PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18752, 5582

Content And Storage

-20°C

Form

Liquid

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Description

  • The PKC family of serine/threonine kinases, including PRKCG (PKC gamma), is activated intracellularly by signal transduction pathways
  • In humans, at least 12 different PKC polypeptides have been identified
  • These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
  • PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
  • Protein kinase C can be activated by calcium and second messenger diacylglycerol
  • PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways
  • PKC also serve as major receptors for phorbol esters, a class of tumor promoters
  • Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells
  • PKC gamma is one of the PKC family members
  • This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons
  • It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase
  • Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development
  • Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

Compare Similar Items

Show Difference

Img

Invitrogen

44-956

--


Antigen:
Phospho-PKC gamma (Thr514)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P05129, P63318

Gene Symbols:
PRKCG

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKC-gamma that contains threonine 514

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
PRKCG

Gene Alias:
PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18752, 5582

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

44-962-G

--


Antigen:
Phospho-PKC alpha (Thr638)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P05696, P17252, P20444

Gene Symbols:
PRKCA

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human PKC that contains threonine 638. The sequence is conserved in mouse and rat.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
PRKCA

Gene Alias:
AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18750, 24680, 5578

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

44-963-G

--


Antigen:
Phospho-PKC beta-1 (Thr642)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P05771

Gene Symbols:
Prkcb

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKCbI that contains threonine 642. The sequence is conserved in rat.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Prkcb

Gene Alias:
A130082F03Rik; Pkcb; PKC-B; PKC-Beta; Prkcb; Prkcb1; PRKCB2; protein kinase C beta; protein kinase C beta I; protein kinase C beta II; protein kinase C beta type; protein kinase C beta-II; protein kinase C, beta; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5579

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

44-964-G

--


Antigen:
Phospho-PKC beta-2 (Thr641)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P05771

Gene Symbols:
PRKCB

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKCbII that contains threonine 641. The sequence is conserved in mouse and rat.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
PRKCB

Gene Alias:
A130082F03Rik; PKCB; PKC-B; PKC-beta; Prkcb; PRKCB1; Prkcb2; protein kinase C beta; protein kinase C beta I; protein kinase C beta II; protein kinase C beta type; protein kinase C beta-II; protein kinase C, beta; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5579

Content And Storage:
-20°C

Form:
Liquid