4544036

Epredia™ Lab Vision™ Cytokeratin 5 Rabbit Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cytokeratin 5, Rabbit Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

Cytokeratin 5

Applications

Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

IVD

Immunogen

A synthetic peptide corresponding to residues on the C-term of human CK5

Clone

EP1601Y

Classification

Monoclonal

Host Species

Rabbit

Research Discipline

Cancer and Tumor Biology

Primary or Secondary

Primary

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Description

  • Twenty human cytokeratins are divided into acidic (pI<5.7) and basic (pI>6.0) subfamilies
  • Members of the acidic and basic subfamilies are found together in pairs
  • The composition of cytokeratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state
  • Many studies have shown the usefulness of cytokeratins as markers in cancer research and tumor identification
  • Point mutations in cytokeratin-5 gene may cause Epidermolysis Bullosa Simplex and Dowling-Degos disease
  • cytokeratin-5 is expressed in most epithelioid and biphasic mesotheliomas, thymoma, squamous and other carcinomas
  • It is related to cytokeratin-6
  • Host Species: Rabbit Clone: EP1601Y Isotype: IgG Species Reactivity: Human
  • Others not known
  • Immunogen: A synthetic peptide corresponding to residues on the C-terminus of human CK5 Molecular Weight: 59 kDa Positive Control: Mesothelioma Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)

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Antigen:
Cytokeratin 5

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
A synthetic peptide corresponding to residues on the C-term of human CK5

Clone:
EP1601Y

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Primary or Secondary:
Primary

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4544042

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Antigen:
Cytokeratin 8/18 Ab-1

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
Cytokeratins purified from breast cancer MCF-7 cells

Clone:
5D3

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cytoskeletal Protein

Primary or Secondary:
Primary

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Fischer Scientific

4544044

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Antigen:
Cytokeratin 8 Ab-4

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation

Conjugate:
__

Regulatory Status:
IVD

Immunogen:
Keratin preparation from a human carcinoma

Clone:
TS1

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cytoskeletal Protein

Primary or Secondary:
Primary

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4544046

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Antigen:
Cytokeratin 8

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
A synthetic peptide corresponding to residues of the human CK18

Clone:
EP1628Y

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Primary or Secondary:
Primary