4544900

Epredia™ Lab Vision™ CD10/CALLA (Neutral Endopeptidase) Ab-2, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD10/CALLA (Neutral Endopeptidase) Ab-2, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

CD10

Applications

Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

IVD

Immunogen

Recombinant external domain of CD10 protein

Clone

56C6

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Oncogenesis

Primary or Secondary

Primary

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Description

  • CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides
  • CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML)
  • It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue
  • CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells
  • Host Species: Mouse Clone: 56C6 Isotype: IgG1 Species Reactivity: Human and Rat
  • Others not tested
  • Epitope: Extracellular Immunogen: Recombinant external domain of CD10 protein Molecular Weight: 100kDa Positive Control: Small intestine Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)

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Antigen:
CD10

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
Recombinant external domain of CD10 protein

Clone:
56C6

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Oncogenesis

Primary or Secondary:
Primary

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Antigen:
CD8 Ab-1

Applications:
__

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule

Clone:
C8/144B

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
T-Cell

Primary or Secondary:
Primary

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4544909

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Antigen:
CD8

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
__

Regulatory Status:
IVD

Immunogen:
Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule

Clone:
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Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
T-Cell

Primary or Secondary:
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Antigen:
__

Applications:
__

Conjugate:
__

Regulatory Status:
__

Immunogen:
__

Clone:
__

Classification:
__

Host Species:
__

Research Discipline:
__

Primary or Secondary:
__