46-714-982

CD215 (IL-15Ra) Monoclonal Antibody (DNT15Ra), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 46-714-982-Each-of-1 In Stock ₹ 34,224.00

46-714-982 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD215 (IL-15Ra)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q60819

Gene Symbols

IL15RA

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16169

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

DNT15Ra

Conjugate

PerCP-eFluor 710

Gene

IL15RA

Gene Alias

AA690181; CD215; IL 15 receptor; IL 15 receptor subunit a; IL 15R; IL 15R alpha; IL 15R a; IL15 receptor; IL15 receptor subunit alpha; IL-15 receptor subunit alpha; IL15 receptor subunit a; IL15R; IL15R alpha; IL15R a; Il15ra; IL-15RA; IL-15R-alpha; Interleukin 15 receptor; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8; interleukin 15 receptor subunit alpha; Interleukin 15 receptor subunit a; interleukin 15 receptor, alpha; interleukin 15 receptor, alpha chain; interleukin-15 receptor subunit alpha; sIL 15R; sIL-15 receptor subunit alpha; sIL15R; sIL-15RA; sIL-15R-alpha; soluble IL 15R; soluble IL15R; Soluble interleukin-15 receptor subunit alpha

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • This DNT15Ra antibody reacts with alpha subunit of Mouse IL-15 Receptor
  • The IL-15 Receptor alpha subunit is unique to IL-15, while the other two subunits of the receptor, beta and gamma, are shared with IL-2
  • IL-15R signaling is mediated by Jak/STAT pathways, and results in the activation of neutrophils, dendritic cells, and macrophages
  • IL-15 has also been found to play a critical role in the development and survival of NK cells and CD8+ T cells
  • Although high levels of mouse IL-15 mRNA have been observed in many cell types, free IL-15 is rarely detectable in biological samples
  • Recent research suggests that IL-15 is retained inside the cell and only secreted in complex with IL-15 Receptor alpha
  • This chaperoning is necessary from the ER to the Golgi, through secretion
  • The cytokine/receptor complex may stay bound to the cell surface, where it can be trans-presented to cells expressing the beta-gamma subunits of the receptor, or can be secreted in a soluble form lacking the transmembrane domain of IL-15 Receptor alpha
  • IL-15 and IL-15 Receptor alpha are expressed by dendritic cells and macrophages in response to inflammatory stimuli
  • Our testing suggests that there may be strain differences in expression and staining of the Mouse IL-15 Receptor alpha
  • This DNT15Ra antibody has been tested on cells from C57Bl/6 mice
  • Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity
  • IL-15 regulates T and natural killer cell activation and proliferation
  • The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding
  • Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits
  • IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.

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Invitrogen

46-714-982

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Antigen:
CD215 (IL-15Ra)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q60819

Gene Symbols:
IL15RA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16169

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
DNT15Ra

Conjugate:
PerCP-eFluor 710

Gene:
IL15RA

Gene Alias:
AA690181; CD215; IL 15 receptor; IL 15 receptor subunit a; IL 15R; IL 15R alpha; IL 15R a; IL15 receptor; IL15 receptor subunit alpha; IL-15 receptor subunit alpha; IL15 receptor subunit a; IL15R; IL15R alpha; IL15R a; Il15ra; IL-15RA; IL-15R-alpha; Interleukin 15 receptor; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8; interleukin 15 receptor subunit alpha; Interleukin 15 receptor subunit a; interleukin 15 receptor, alpha; interleukin 15 receptor, alpha chain; interleukin-15 receptor subunit alpha; sIL 15R; sIL-15 receptor subunit alpha; sIL15R; sIL-15RA; sIL-15R-alpha; soluble IL 15R; soluble IL15R; Soluble interleukin-15 receptor subunit alpha

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
TNF alpha

Classification:
Monoclonal

Concentration:
0.2 mg/mL

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PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P06804

Gene Symbols:
Tnf

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21926

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MP6-XT22

Conjugate:
PerCP-eFluor 710

Gene:
Tnf

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

R&D Systems™

46-750-9601

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store the unopened product at 2 to 8°C

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
6 mL

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

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R&D Systems™

46-750-9602

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store the unopened product at 2 to 8°C

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
6 mL

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__