46-991-741

CD284 (TLR4) Monoclonal Antibody (HTA125), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each 46-991-741-Each In Stock ₹ 13,574.09

46-991-741 - Each

₹ 13,574.09

In Stock

Quantity

1

Base Price: ₹ 13,574.09

GST (18%): ₹ 2,443.336

Total Price: ₹ 16,017.426

Antigen

CD284 (TLR4)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

O00206

Gene Symbols

TLR4

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7099

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

HTA125

Conjugate

PerCP-eFluor 710

Gene

TLR4

Gene Alias

ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species

Mouse

Quantity

25 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
  • Mammalian cells respond to LPS by activating TLR4
  • TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
  • TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
  • Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
  • TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
  • Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
  • Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

46-991-741

--


Antigen:
CD284 (TLR4)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
O00206

Gene Symbols:
TLR4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7099

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HTA125

Conjugate:
PerCP-eFluor 710

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

46-991-742

--


Antigen:
CD284 (TLR4)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
O00206

Gene Symbols:
TLR4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7099

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HTA125

Conjugate:
PerCP-eFluor 710

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

46-996-941

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Antigen:
CD279 (PD-1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q15116

Gene Symbols:
Pdcd1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5133

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MIH4

Conjugate:
PerCP-eFluor 710

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

46-997-282

--


Antigen:
CD273 (B7-DC)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9WUL5

Gene Symbols:
PDCD1LG2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
58205

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
122

Conjugate:
PerCP-eFluor 710

Gene:
PDCD1LG2

Gene Alias:
B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; F730015O22Rik; MGC124039; MGC124040; PD1 ligand 2; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; Pdl2; PD-L2; Programmed cell death 1 ligand 2; programmed death ligand 2

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ