4775390
CD11b/Mac-1 Mouse anti-Human, BUV395, Clone: ICRF44 (also known as 44), BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD11b
Applications
Flow Cytometry
Conjugate
Brilliant Ultraviolet 395
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
Mac-1α, integrin αM subunit, CR3 α chain
Clone
ICRF44 (also known as 44)
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human monocytes
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β 2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3
- CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells
- CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3)
- This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP
- The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument
- With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector
- BD Horizon™ BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.
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Antigen: CD11b
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 395
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: Mac-1α, integrin αM subunit, CR3 α chain
Clone: ICRF44 (also known as 44)
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human monocytes
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD11b
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 395
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
Mac-1α, integrin αM subunit, CR3 α chain
Clone:
ICRF44 (also known as 44)
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human monocytes
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Formulation: __
Isotype: __
Purification Method: __
Description: __
Clone: __
Classification: __
Host Species: __
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Immunogen: __
Primary or Secondary: __
Content And Storage: __
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Conjugate:
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Immunogen:
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Primary or Secondary:
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Content And Storage:
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Purification Method: __
Description: __
Clone: __
Classification: __
Host Species: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: Store the unopened product at 2 - 8° C. Do not use past expiration date.
Antigen:
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Applications:
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Conjugate:
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Regulatory Status:
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Formulation:
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Isotype:
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Purification Method:
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Description:
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Clone:
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Classification:
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Host Species:
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Target Species:
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
Store the unopened product at 2 - 8° C. Do not use past expiration date.
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Formulation: __
Isotype: __
Purification Method: __
Description: __
Clone: __
Classification: __
Host Species: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: Store the unopened product at -20 to -70° C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Antigen:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Formulation:
__
Isotype:
__
Purification Method:
__
Description:
__
Clone:
__
Classification:
__
Host Species:
__
Target Species:
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
Store the unopened product at -20 to -70° C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.