48-028-942
CD28 Monoclonal Antibody (CD28.2), eFluor™ 450, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 48-028-942-Each-of-1 | In Stock | ₹ 28,234.80 |
48-028-942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,234.80
GST (18%): ₹ 5,082.264
Total Price: ₹ 33,317.064
Antigen
CD28
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P10747
Gene Symbols
Cd28
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
940
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
CD28.2
Conjugate
eFluor 450
Gene
Cd28
Gene Alias
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The CD28.2 monoclonal antibody reacts with the human CD28 molecule, a 44 kDa homodimer expressed by thymocytes, mature T cells and plasma cells
- CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) and is a potent co-stimulator of T cells
- Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells
- Applications Reported: This CD28.2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This CD28.2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.125 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- eFluor™ 450 is an alternative to Pacific Blue™
- eFluor™ 450 emits at 445 nm and is excited with the Violet laser (405 nm)
- Please make sure that your instrument is capable of detecting this fluorochome
- Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser
- Filtration: 0.2 μm post-manufacturing filtered
- CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein
- CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes
- Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells
- In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death
- In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28
- In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR
- The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells
- Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary's Disease.
Compare Similar Items
Show Difference
Antigen: CD28
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P10747
Gene Symbols: Cd28
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 940
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CD28.2
Conjugate: eFluor 450
Gene: Cd28
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD28
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P10747
Gene Symbols:
Cd28
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
940
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CD28.2
Conjugate:
eFluor 450
Gene:
Cd28
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD38
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P28907
Gene Symbols: CD38
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 952
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: HIT2
Conjugate: eFluor 450
Gene: CD38
Gene Alias: 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD38
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P28907
Gene Symbols:
CD38
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
952
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
HIT2
Conjugate:
eFluor 450
Gene:
CD38
Gene Alias:
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: Supplied as a trifluoroacetate salt.
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: Hygroscopic, Protect from light
Form: Lyophilized
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 1 mg
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
Supplied as a trifluoroacetate salt.
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
Hygroscopic, Protect from light
Form:
Lyophilized
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
1 mg
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__
Antigen: __
Classification: __
Concentration: __
Formulation: Supplied as a trifluoroacetate salt.
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: Hygroscopic, Protect from light
Form: Solid
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 2 mg
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
Supplied as a trifluoroacetate salt.
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
Hygroscopic, Protect from light
Form:
Solid
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
2 mg
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__