4971483

Caspase-1 Antibody (14F468) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 54 publications

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Caspase-1

Concentration

1.0 mg/mL

Applications

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Apoptosis, Caspases

Gene Accession No.

P29466

Gene ID (Entrez)

834

Immunogen

A synthetic peptide corresponding to amino acids 371-390 RKVRFSFEQPDGRAQMPTTE of human caspase-1 was used as immunogen.

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen

45 kDa

Clone

14F468

Dilution

Western Blot 0.5-2 ug/ml, Simple Western 1:50, Immunohistochemistry 1:100 - 1:500, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen reported in scientific literature (PMID 30930743)

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Mouse, Rat

Gene Alias

CASP-1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, caspase-1, EC 3.4.22, EC 3.4.22.36, ICEP45, IL-1 beta-converting enzyme, IL-1BC, IL1BC CASP1 nirs variant 1, IL1BCE, IL1B-convertase, interleukin 1-B converting enzyme, interleukin 1-beta convertase, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45

Gene Symbols

CASP1

Isotype

IgG1 κ

Purification Method

Protein G purified

Test Specificity

The antibody will recognize full-length Caspase-1 and cleaved caspase-1 forms that retain amino acids 371-390 of the Caspase-1 protein.

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Description

  • Caspase-1 Monoclonal specifically detects Caspase-1 in Human, Mouse, Rat samples
  • It is validated for Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

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4971483

Mouse Monoclonal Antibody has been ...


Antigen:
Caspase-1

Concentration:
1.0 mg/mL

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Caspases

Gene Accession No.:
P29466

Gene ID (Entrez):
834

Immunogen:
A synthetic peptide corresponding to amino acids 371-390 RKVRFSFEQPDGRAQMPTTE of human caspase-1 was used as immunogen.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
45 kDa

Clone:
14F468

Dilution:
Western Blot 0.5-2 ug/ml, Simple Western 1:50, Immunohistochemistry 1:100 - 1:500, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen reported in scientific literature (PMID 30930743)

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Gene Alias:
CASP-1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, caspase-1, EC 3.4.22, EC 3.4.22.36, ICEP45, IL-1 beta-converting enzyme, IL-1BC, IL1BC CASP1 nirs variant 1, IL1BCE, IL1B-convertase, interleukin 1-B converting enzyme, interleukin 1-beta convertase, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45

Gene Symbols:
CASP1

Isotype:
IgG1 κ

Purification Method:
Protein G purified

Test Specificity:
The antibody will recognize full-length Caspase-1 and cleaved caspase-1 forms that retain amino acids 371-390 of the Caspase-1 protein.

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4971507

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Antigen:
Caspase-2

Concentration:
__

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Cancer, Caspases

Gene Accession No.:
P42575

Gene ID (Entrez):
835

Immunogen:
A peptide corresponding to amino acids 400-450 of human Caspase-2 was used as immunogen. GenBank no NP_116764.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
__

Clone:
18E809.3

Dilution:
Western Blot 1:500-1:1000

Classification:
Monoclonal

Form:
Ascites

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
caspase-2, CASP-2, caspase 2, apoptosis-related cysteine peptidase, ICH1, NEDD2, NEDD-2, PPP1R57

Gene Symbols:
CASP2

Isotype:
IgM κ

Purification Method:
Unpurified

Test Specificity:
In HL60, a 48 kDa band is observed. This will cross-react with mouse and rat Caspase-2, based on BLAST.

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Antigen:
Caspase-3

Concentration:
1.0 mg/mL

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Cancer, Caspases

Gene Accession No.:
P42574

Gene ID (Entrez):
836

Immunogen:
This Caspase-3 Antibody (CPP32 4-1-18) was developed against full-length recombinant human Caspase 3 [UniProt# P42574].

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
31.7 kDa

Clone:
CPP32 4-1-18

Dilution:
Western Blot 1:500-1:1000, Simple Western 1:2000, Immunohistochemistry 1:200-1:500, Immunocytochemistry/Immunofluorescence 2 ug/ml, Immunoprecipitation 2 ug/ mg lysate, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen reported in scientific literature (PMID 31242448)

Classification:
Monoclonal

Form:
Ascites

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Gene Alias:
Apopain, apoptosis-related cysteine protease, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama

Gene Symbols:
CASP3

Isotype:
IgG2a κ

Purification Method:
Protein G purified

Test Specificity:
__

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4971590

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Antigen:
Caspase-7

Concentration:
__

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Cancer, Caspases, Cell Biology, Ubiquitin Proteasome Pathway

Gene Accession No.:
P55210

Gene ID (Entrez):
840

Immunogen:
Full-length recombinant human Caspase 7 [UniProt# P55210]

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
35 kDa

Clone:
Mch3 1-1-11

Dilution:
Western Blot 1:500-1:1000, Simple Western 1:500

Classification:
Monoclonal

Form:
Ascites

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Gene Alias:
apoptosis-related cysteine protease, Apoptotic protease Mch-3, CASP-7, caspase 7, apoptosis-related cysteine peptidase, caspase-7, EC 3.4.22, EC 3.4.22.60, ICE-like apoptotic protease 3, Lice2 alpha/beta/gamma

Gene Symbols:
CASP7

Isotype:
IgG1 κ

Purification Method:
Unpurified

Test Specificity:
__