50-100-2514

SIAH2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-100-2514-Each-of-1 In Stock ₹ 42,443.75

50-100-2514 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

SIAH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SIAH2

Gene Alias

hSiah2, Seven in absentia homolog 2, Siah 2, SIAH2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

140593, 20439, 6478

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.27 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

O43255, Q06986, Q8R4T2

Gene Symbols

SIAH2

Immunogen

SIAH2 Fusion Protein Ag3342

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • SIAH-2 (seven in absentia homolog 2) is an E3 ligase that catalyzes ubiquitination and proteasome-mediated degradation of protein substrates
  • SIAH-2 encodes a 324 amino acid protein that shares 77% identity with human SIAH-1 and 68% identity with the Drosophila sina (seven in absentia) gene, on which development of the Drosophila R7 photoreceptor is dependent
  • SIAH-2 targets TRAF2 (which regulates cell responses to stress and cytokines through the regulation of key stress-signaling cascades) for degradation under stress conditions such as hypoxia
  • It targets HIF-1 alpha prolyl hydroxylase 3 (PHD3) for degradation upon exposure to hypoxic conditions, which coincides with an increase in SIAH-2 transcription
  • SIAH-2 can decrease TNF-alpha-dependent induction of JNK activity and transcriptional activation of NFkB
  • SIAH-2 null mice subjected to hypoxia display an impaired respiratory response and reduced levels of hemoglobin.

Compare Similar Items

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Img

Proteintech Group Inc

50-100-2514

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Antigen:
SIAH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIAH2

Gene Alias:
hSiah2, Seven in absentia homolog 2, Siah 2, SIAH2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140593, 20439, 6478

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O43255, Q06986, Q8R4T2

Gene Symbols:
SIAH2

Immunogen:
SIAH2 Fusion Protein Ag3342

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Proteintech Group Inc

50-100-2529

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Antigen:
DNAJB9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAJB9

Gene Alias:
DNAJB9, ERdj4, Mdg 1, MDG1, MST049, MSTP049

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24908, 27362, 4189

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P97554, Q9QYI6, Q9UBS3

Gene Symbols:
DNAJB9

Immunogen:
DNAJB9 Fusion Protein Ag3789

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-100-2533

--


Antigen:
NMNAT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NMNAT3

Gene Alias:
NaMN adenylyltransferase 3, NMNAT3, PNAT 3, PNAT3

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
349565, 363118, 74080

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q96T66, Q99JR6

Gene Symbols:
NMNAT3

Immunogen:
NMNAT3 Fusion Protein Ag3965

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-100-2590

--


Antigen:
gamma Tubulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TUBG1

Gene Alias:
Gamma 1 tubulin, gamma Tubulin, GCP 1, TUBG, TUBG1, TUBGCP1, Tubulin gamma 1 chain, tubulin, gamma 1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
103733, 252921, 403695, 7283

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P23258, P83887, P83888, Q9GKK5

Gene Symbols:
TUBG1

Immunogen:
gamma Tubulin Fusion Protein Ag7070

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG