50-112-2138

TCR V alpha 3.2 Monoclonal Antibody (RR3-16), FITC, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2138-Each-of-1 In Stock ₹ 7,593.45

50-112-2138 - Each of 1

₹ 7,593.45

In Stock

Quantity

1

Base Price: ₹ 7,593.45

GST (18%): ₹ 1,366.821

Total Price: ₹ 8,960.271

Antigen

TCR V alpha 3.2

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

RR3-16

Conjugate

FITC

Gene Alias

TCR V alpha3.2; TCRV alpha 3.2; TCRV alpha3.2; Va3.2; Valpha3.2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • Description: This RR3-16 monoclonal antibody reacts with the mouse T cell receptor (TCR) V alpha 3.2 chain
  • Composed of an alpha and beta chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement
  • The RR3-16 antibody recognizes the V alpha 3.2 chain on T cells from mouse strains bearing the b (e.g., C57BL/6) or c haplotype (e.g., SJL, SWR, and NOD) in the Tcra gene complex
  • The V alpha 3.2 chain is absent in mice with the a (e.g., Balb/c, AKR, C3H) and d (e.g., DBA/1 and DBA/2) haplotypes
  • Studies demonstrate that the V alpha 3.2 TCR is more highly expressed on CD8+ T cells
  • Applications Reported: This RR3-16 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This RR3-16 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.125 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
  • TCR recognition of self-peptides has been linked to autoimmune disease
  • Mutant self-peptides have been associated with tumors
  • Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
  • Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
  • The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease
  • Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
  • A small number of T cells lack both CD4 and CD8 (double negative, DN)
  • Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
  • Gamma-delta T cells are primarily found within the epithelium
  • They show less TCR diversity and recognize antigens differently than alpha-beta T cells
  • Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Compare Similar Items

Show Difference

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Invitrogen

50-112-2138

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Antigen:
TCR V alpha 3.2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
RR3-16

Conjugate:
FITC

Gene Alias:
TCR V alpha3.2; TCRV alpha 3.2; TCRV alpha3.2; Va3.2; Valpha3.2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Invitrogen

50-112-2149

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Antigen:
MHC Class II

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Host Species:
Rat

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
YKIX334.2

Conjugate:
FITC

Gene Alias:
beta 1 domain; B-L; B-L beta chain; B-L beta minor; B-LB; BLB major; BLB1; BLB2; B-LB2; B-LB21; B-LB21 major; BLB3; Bl-Beta II protein; B-LBII; class II histocompatibility antigen, B-L beta chain; class II histocompatibility antigen, M alpha chain; D6S222E; DMA; FECA-DRB; GSP-BLB1; GSP-BLB2; HLA class II histocompatibility antigen, DM alpha chain; HLADM; HLA-DMA; major histocompatibility class II antigen B-L beta; major histocompatibility complex class II B; Major histocompatibility complex class II beta chain BLB1; Major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain); major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain); Major histocompatibility complex class II beta chain BLB2, (similar to HLA class II, D beta chain); Major histocompatibility complex class II beta chain BLB3, (similar to HLA class II, D beta chain); major histocompatibility complex, class II, DM alpha; MHC 2; MHC Class II; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen B-F minor heavy chain; MHC class II antigen DMA; MHC class II antigen DRB; MHC Class II beta 1 and 2 domains; MHC class II beta 1 domain; MHC class II beta chain; MHC class II beta chain 1; MHC class II beta chain 2; MHC class II B-L beta chain; MHC II; MHCCII; MHCFECA-DRB; really interesting new gene 6 protein; RING6; S19; uncharacterized protein LOC101747454

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Canine

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

50-112-2152

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Antigen:
MHC Class I (H-2Kb)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
AF6-88.5.5.3

Conjugate:
FITC

Gene Alias:
class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

50-112-2155

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Antigen:
IL-13

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
85BRD

Conjugate:
FITC

Gene Alias:
ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ