50-112-2321
CD218a (IL-18Ra) Monoclonal Antibody (P3TUNYA), PE, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-2321-Each-of-1 | In Stock | ₹ 32,170.56 |
50-112-2321 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,170.56
GST (18%): ₹ 5,790.701
Total Price: ₹ 37,961.261
Antigen
CD218a (IL-18Ra)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q61098
Gene Symbols
Il18r1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16182
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
P3TUNYA
Conjugate
PE
Gene
Il18r1
Gene Alias
CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Description
- Description: This P3TUNYA monoclonal antibody reacts with mouse CD218a (Interleukin 18 Receptor alpha)
- CD218a is one of the subunits of the heterodimeric receptor complex for the IL-18 cytokine
- IL-18 is a proinflammatory cytokine and member of the IL-1 family first identified by its role in IFN gamma secretion during toxic shock
- Like the other members of the family, it is synthesized as an inactive precursor which requires cleavage by caspases prior to secretion of the active form
- It is secreted by activated monocytes, macrophages, epithelial cells, and keratinocytes via a non-classical pathway
- IL-18 Receptor is expressed on Th1, but not naive CD4 T cells or Th2, as well as subsets of NK cells and neutrophils
- The heterodimeric receptor is made up of a ligand-binding alpha chain and signal-transducing beta chain
- On its own, IL-18Ra binds IL-18 with low affinity, although the affinity of this interaction increases upon forming a complex with IL-18Rb
- IL-18R signaling plays a critical role in Th1 differentiation and effector function, and results in the increased expression of IFN gamma, TNF alpha, and Fas ligand from T cells and NK cells
- IL-18 has also been found to synergize with IL-23 in the development and function of Th17 cells
- Recently, a subset of CD8 T cells has been discovered that co-secretes IFN gamma with IL-17A and sometimes IL-22
- These Tc17 cells share key transcription factors, chemokine receptors, and cytokine receptors with Th17 cells
- IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family
- This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction
- IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells
- The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
Compare Similar Items
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Antigen: CD218a (IL-18Ra)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q61098
Gene Symbols: Il18r1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16182
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: P3TUNYA
Conjugate: PE
Gene: Il18r1
Gene Alias: CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD218a (IL-18Ra)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q61098
Gene Symbols:
Il18r1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16182
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
P3TUNYA
Conjugate:
PE
Gene:
Il18r1
Gene Alias:
CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: MHC Class II I-Ab
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P01921, P06342, P06343, P06344, P06345, P06346, P14483
Gene Symbols: H2-Ab1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14961
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: AF6-120.1
Conjugate: PE
Gene: H2-Ab1
Gene Alias: Abeta; AI845868; CELIAC1; DADB-249P12.2; H-2 class II histocompatibility antigen, A beta chain; H-2Ab; H2-Ab; H2-Ab1; H2Eb; H-2Eb; H2-iabeta; histocompatibility 2, class II antigen A, beta 1; HLA-DQB; Ia2; Ia-2; Ia4; Ia-4; IAb; I-Abeta; IDDM1; major histocompatibility complex class II beta chain; MGC163794; MGC163796; MHC class II antigen A beta; MHC class II H2-IA-beta-psi; response to metastatic cancers 1; Rmcs1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
MHC Class II I-Ab
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P01921, P06342, P06343, P06344, P06345, P06346, P14483
Gene Symbols:
H2-Ab1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14961
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
AF6-120.1
Conjugate:
PE
Gene:
H2-Ab1
Gene Alias:
Abeta; AI845868; CELIAC1; DADB-249P12.2; H-2 class II histocompatibility antigen, A beta chain; H-2Ab; H2-Ab; H2-Ab1; H2Eb; H-2Eb; H2-iabeta; histocompatibility 2, class II antigen A, beta 1; HLA-DQB; Ia2; Ia-2; Ia4; Ia-4; IAb; I-Abeta; IDDM1; major histocompatibility complex class II beta chain; MGC163794; MGC163796; MHC class II antigen A beta; MHC class II H2-IA-beta-psi; response to metastatic cancers 1; Rmcs1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Podoplanin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q62011
Gene Symbols: PDPN
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14726
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio8.1.1 (8.1.1)
Conjugate: PE
Gene: PDPN
Gene Alias: 29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein
Host Species: Syrian Hamster
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Podoplanin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q62011
Gene Symbols:
PDPN
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14726
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio8.1.1 (8.1.1)
Conjugate:
PE
Gene:
PDPN
Gene Alias:
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein
Host Species:
Syrian Hamster
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: BCL6
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P41183
Gene Symbols: BCL6
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12053
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: BCL-DWN
Conjugate: PE
Gene: BCL6
Gene Alias: B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; Bcl6; Bcl-6; BCL6 transcription repressor; BCL6A; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S; ZNF51
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
BCL6
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P41183
Gene Symbols:
BCL6
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12053
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
BCL-DWN
Conjugate:
PE
Gene:
BCL6
Gene Alias:
B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; Bcl6; Bcl-6; BCL6 transcription repressor; BCL6A; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S; ZNF51
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ