50-112-2577

CD338 (ABCG2) Monoclonal Antibody (5D3), Biotin, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2577-Each-of-1 In Stock ₹ 24,042.36

50-112-2577 - Each of 1

₹ 24,042.36

In Stock

Quantity

1

Base Price: ₹ 24,042.36

GST (18%): ₹ 4,327.625

Total Price: ₹ 28,369.985

Antigen

CD338 (ABCG2)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9UNQ0

Gene Symbols

ABCG2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9429

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

5D3

Conjugate

Biotin

Gene

ABCG2

Gene Alias

ABC transporter; ABC15; Abcg2; ABCP; AI428558; ATP binding cassette subfamily G member 2 (Junior blood group); ATP-binding cassette sub-family G member 2; ATP-binding cassette transporter G2; ATP-binding cassette, sub-family G (WHITE), member 2; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group); BCRP; Bcrp1; BMDP; Breast cancer resistance protein; breast cancer resistance protein 1 homolog; Broad substrate specificity ATP-binding cassette transporter ABCG2; CD338; CDw338; EST157481; GOUT1; mitoxantrone resistance protein 1; mitoxantrone resistance-associated protein; MRX; multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2; MXR; MXR1; MXR-1; placenta specific MDR protein; placenta-specific ATP-binding cassette transporter; UAQTL1; Urate exporter

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Related Products

Img

Invitrogen

50-112-2400

--

Img

Invitrogen

46-036-941

--

Img

Invitrogen

42-780-0

--

Img

Invitrogen

40-980-0

--

Img

Invitrogen

44-298-G

--

Img

Invitrogen

41-210-0

--

Img

Invitrogen

50-110-91

--

Img

Invitrogen

50-100-05

--

Description

  • Description: The 5D3 monoclonal antibody reacts with the extracellular portion of the human ABCG2 protein, also known as Bcrp1 and MXR
  • The ABCG2 gene, a member of the multi-drug resistance (MDR) family, is highly expressed on primitive 'side-population' (SP) stem cells, which are defined by the efflux of fluorescent dyes such as Rhodamine 123 and Hoechest 33342
  • In the bone marrow, about 0.05% of cells display the low fluorescence and are highly enriched for repopulating cells
  • The SP cells, which express low or undetectable levels of CD34, have been identified in multiple species
  • In addition, expression of ABCG2 appears to be highly conserved
  • Applications Reported: The 5D3 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: The 5D3 antibody has been tested by flow cytometric analysis of human ABCG2 transfected cells and normal human peripheral blood cells
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Filtration: 0.2 μm post-manufacturing filtered
  • ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1)
  • ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan
  • Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation
  • ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker
  • ABCG2 may have N-linked glycosylation and may dimerize in vivo
  • ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.

Compare Similar Items

Show Difference

Img

Invitrogen

50-112-2577

--


Antigen:
CD338 (ABCG2)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9UNQ0

Gene Symbols:
ABCG2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9429

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
5D3

Conjugate:
Biotin

Gene:
ABCG2

Gene Alias:
ABC transporter; ABC15; Abcg2; ABCP; AI428558; ATP binding cassette subfamily G member 2 (Junior blood group); ATP-binding cassette sub-family G member 2; ATP-binding cassette transporter G2; ATP-binding cassette, sub-family G (WHITE), member 2; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group); BCRP; Bcrp1; BMDP; Breast cancer resistance protein; breast cancer resistance protein 1 homolog; Broad substrate specificity ATP-binding cassette transporter ABCG2; CD338; CDw338; EST157481; GOUT1; mitoxantrone resistance protein 1; mitoxantrone resistance-associated protein; MRX; multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2; MXR; MXR1; MXR-1; placenta specific MDR protein; placenta-specific ATP-binding cassette transporter; UAQTL1; Urate exporter

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Invitrogen

50-112-2595

--


Antigen:
APP (Amyloid Precursor Protein)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P05067, P08592, P12023

Gene Symbols:
APP

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11820, 351, 54226

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Clone:
22C11

Conjugate:
Biotin

Gene:
APP

Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; amyloid A4; Amyloid b precursor protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid β precursor protein; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

50-112-26

--


Antigen:
TRA-1-60 (Podocalyxin)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
TRA-1-60

Conjugate:
PE

Gene:
__

Gene Alias:
TRA160; tra60

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM

Img

Fischer Scientific

50-112-2606

--


Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P06332

Gene Symbols:
CD4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12504

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4SM95

Conjugate:
Biotin

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ