50-112-2694
MASH1 Monoclonal Antibody (24B72D11), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-2694-Each-of-1 | In Stock | ₹ 32,512.80 |
50-112-2694 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,512.80
GST (18%): ₹ 5,852.304
Total Price: ₹ 38,365.104
Antigen
MASH1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P19359, Q02067
Gene Symbols
Ascl1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17172, 64186
Content And Storage
4° C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
24B72D11
Conjugate
Unconjugated
Gene
Ascl1
Gene Alias
achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; achaete-scute homolog 1; AI225900; Ascl1; ASH1; ASH-1; bHLHa46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; mammalian achaete scute homolog 1; Mash1; mASH-1
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Description
- Description: The monoclonal antibody 24B72D11 recognizes mouse and rat Mammalian achaete-scute homolog 1 (MASH1), a 34 kDa basic helix-loop-helix (bHLH) transcription factor
- MASH1, like family members Olig2 and Ngn2, is expressed in progenitor cells throughout the nervous system and retina and is a key regulator of cell fate specification
- Expression of MASH1 is regulated by the Delta/Notch1 pathway through direct binding of Hes1 to MASH1 as well as competitive binding to MASH1 hetero-dimerizing proteins
- At a transcriptional level, MASH1 expression is controlled by notch-mediated regulation of sox2, which binds to the MASH1 promoter region up-regulating expression
- MASH1 has been implicated in the formation of multiple neural cell types including dopaminergic, serotonergic, glutaminergic and GABAergic neurons
- Overexpression of MASH1 has been shown in small cell lung carcinoma and medullary thyroid cancer
- Applications Reported: This 24B72D11 antibody has been reported for use in western blotting, immunohistochemical staining of frozen tissue sections, and immunocytochemistry
- Applications Tested: This 24B72D11 antibody has been tested by western blot on reduced PC12 cells and can be used at less than or equal to 5 μg/mL
- The 24B72D11 antibody has also been tested by immunocytochemistry on fixed and permeablized PC12 cells at can be used at less than or equal to 20 μg/mL
- ASCL1 (also known as ASH1) is a basic helix-loop-helix transcription factor that is required for early development of the nervous system
- Expressed in fetal brain, ASCL1 is essential for the proper development of autonomic neurons and for the survival of subsets of autonomic neurons
- ASCL1 interaction with MEF-2A may regulate the expression of specific genes that are critical for the formation of distinct neuronal circuits within the central nervous system
- The high level of ASCL1 expression in neuroendocrine tumors, such as medullary thyroid cancer, small cell lung cancer and lung cancer with neuroendocrine features may provide a useful marker for cancers with neuroendocrine features
- Mapping to human chromosome 12, the ASCL1 gene contains a trinucleotide repeat region, making this locus a candidate for inherited disease.
Compare Similar Items
Show Difference
Antigen: MASH1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P19359, Q02067
Gene Symbols: Ascl1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17172, 64186
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: 24B72D11
Conjugate: Unconjugated
Gene: Ascl1
Gene Alias: achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; achaete-scute homolog 1; AI225900; Ascl1; ASH1; ASH-1; bHLHa46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; mammalian achaete scute homolog 1; Mash1; mASH-1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
MASH1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P19359, Q02067
Gene Symbols:
Ascl1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17172, 64186
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone:
24B72D11
Conjugate:
Unconjugated
Gene:
Ascl1
Gene Alias:
achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; achaete-scute homolog 1; AI225900; Ascl1; ASH1; ASH-1; bHLHa46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; mammalian achaete scute homolog 1; Mash1; mASH-1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: FceR1 alpha
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P20489
Gene Symbols: FCER1A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14125
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: MAR-1
Conjugate: Unconjugated
Gene: FCER1A
Gene Alias: alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3
Host Species: Armenian Hamster
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
FceR1 alpha
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P20489
Gene Symbols:
FCER1A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14125
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
MAR-1
Conjugate:
Unconjugated
Gene:
FCER1A
Gene Alias:
alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3
Host Species:
Armenian Hamster
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: iNOS
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P29477
Gene Symbols: Nos2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18126
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: CXNFT
Conjugate: Unconjugated
Gene: Nos2
Gene Alias: Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
iNOS
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P29477
Gene Symbols:
Nos2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18126
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
CXNFT
Conjugate:
Unconjugated
Gene:
Nos2
Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Myosin 4
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene Symbols: MYH4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: MF20
Conjugate: Unconjugated
Gene: MYH4
Gene Alias: 2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Host Species: Mouse
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Myosin 4
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene Symbols:
MYH4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
MF20
Conjugate:
Unconjugated
Gene:
MYH4
Gene Alias:
2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Host Species:
Mouse
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG2b κ