50-112-2883

PU.1 Monoclonal Antibody (phpu13), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2883-Each-of-1 In Stock ₹ 35,935.20

50-112-2883 - Each of 1

₹ 35,935.20

In Stock

Quantity

1

Base Price: ₹ 35,935.20

GST (18%): ₹ 6,468.336

Total Price: ₹ 42,403.536

Antigen

PU.1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P17433, P17947

Gene Symbols

SPI1

Immunogen

E. coli-derived protein, without DNA domain

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

phpu13

Conjugate

Unconjugated

Gene

SPI1

Gene Alias

31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20375, 6688

Content And Storage

4° C

Form

Liquid

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Description

  • Description: The monoclonal phpu13 recognizes human and mouse PU.1, a member of the ets family of transcription factors
  • This 42 kDa protein was originally identified as Spi-1, a proto-oncogene, for its role in Friend virus-induced murine erythroleukemia
  • Expression of PU.1 plays a critical role in lymphocyte and myeloid development
  • Knock-out mice are neonatal lethal and lack myeloid, T and B cells
  • In addition erythroid development is also altered
  • Protein expression levels help guarantee proper development; higher levels in myeloid cells compared to lymphocytes
  • PU.1 controls transcription of several proteins including CD11b, CD18, Gata2, IRF4, CD20, CD10, and CD79
  • Disruption of PU.1 expression may play a role in several specific leukemias; such as B-chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, T-cell rich B-cell lymphoma, and nodular lymphocyte predomit Hodgkin
  • Applications Reported: This phpu13 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections and immunocytochemistry
  • Applications Tested: This phpu13 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded tissue using IHC Antigen Retrieval Solution - Low pH (10X) (cat
  • 00-4955)
  • This can be used at less than or equal to 10 μg/mL
  • This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development
  • The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors
  • The protein can also regulate alternative splicing of target genes
  • Multiple transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

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Invitrogen

50-112-2883

--


Antigen:
PU.1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P17433, P17947

Gene Symbols:
SPI1

Immunogen:
E. coli-derived protein, without DNA domain

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
phpu13

Conjugate:
Unconjugated

Gene:
SPI1

Gene Alias:
31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20375, 6688

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

50-112-2886

--


Antigen:
Cutaneous Lymphocyte Antigen (CLA)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM κ

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin), Western Blot

Clone:
HECA-452

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
CLA

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

50-112-2899

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Antigen:
TCR alpha/beta

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01848, P04435

Gene Symbols:
TRA, TRAC, TRB, TRBV7-9

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
IP26

Conjugate:
Unconjugated

Gene:
TRBV7-9

Gene Alias:
FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
28589, 28755, 6955, 6957

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

50-112-2901

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Antigen:
CD3e

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P04235, P11942, P22646, P24161

Gene Symbols:
Cd247, Cd3d, CD3E, CD3g

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
145-2C11

Conjugate:
PE-Cyanine5

Gene:
Cd247

Gene Alias:
4930549J05Rik; A430104F18Rik; AI504783; antigen CD3D, delta polypeptide (TiT3 complex); antigen CD3E, epsilon polypeptide (TiT3 complex); antigen CD3G, gamma polypeptide; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; CD3; CD3 antigen delta chain; CD3 antigen delta polypeptide; CD3 antigen gamma chain; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 antigen, zeta polypeptide; CD3 delta; CD3 epsilon; CD3 epsilon chain; CD3 epsilon subunit; CD3 epsilon subunit precursor; CD3 gamma-chain; CD3 glycoprotein; CD3 glycoprotein precursor; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; CD3 protein; CD3 TCR complex; CD3 type I transmembrane glycoprotein; CD3 type I transmembrane glycoprotein precursor; CD3 zeta chain; Cd3d; CD3D antigen delta; CD3D antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3E antigen, epsilon polypeptide; CD3E antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; Cd3-eta; Cd3g; CD3G antigen, gamma polypeptide; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Cd3h; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; Ctg3; Ctg-3; FLJ18683; IMD17; IMD18; IMD19; IMD25; Leu-4; OKT3, delta chain; T cell antigen receptor complex epsilon subunit of T3; T3/TCR complex; T3d; T3e; T3g; T3Z; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 epsilon chain; T-cell receptor CD3 epsilon subunit; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 delta chain; T-cell receptor T3 eta chain; T-cell receptor T3 gamma chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; T-cell surface glycoprotein CD3 zeta chain; T-cell surface protein; TcR CD3 delta-chain; TcR CD3 gamma-chain; TCR zeta chain; TCR zeta chain subunit; TCRE; Tcrk; TCRZ; TCRzeta; TiT3 complex; type I transmembrane protein; T-cell surface molecule CD3

Host Species:
Armenian Hamster

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12500, 12501, 12502, 12503

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid