50-112-3070
CD112 (Nectin-2) Monoclonal Antibody (R2.477), APC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-3070-Each-of-1 | In Stock | ₹ 31,657.20 |
50-112-3070 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,657.20
GST (18%): ₹ 5,698.296
Total Price: ₹ 37,355.496
Antigen
CD112 (Nectin-2)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q92692
Gene Symbols
NECTIN2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5819
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
R2.477
Conjugate
APC
Gene
NECTIN2
Gene Alias
AI325026; AI987993; CD112; herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; MPH; Murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin cell adhesion molecule 2; Nectin2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; poliovirus sensitivity; PRR2; Pvr; Pvrl2; PVRR2; Pvs
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: This R2.477 monoclonal antibody reacts with human CD112 (also known as Nectin-2 or Poliovirus Receptor Related 2), a 60-65 kDa immunoglobulin-like transmembrane cell adhesion molecule
- This cell surface molecule is expressed on hematopoietic cells, endothelial, epithelial, as well as tumor cell lines such as Jurkat, U937, and MCF7
- CD112 is a ligand for DNAM-1 (CD226), a leukocyte adhesion molecule expressed on natural killer (NK) cells
- Interaction between CD112 and DNAM-1 promotes NK cytotoxic activity, leading to tumor cell lysis
- In addition to its role in tumor suppression, CD112 plays a cooperative role in cell-cell adhesion, particularly in the formation of adherens junctions between neighboring epithelial cells and fibroblasts
- CD112 can form homophilic and heterophilic interactions to regulate contact inhibition of cell movement and proliferation
- Finally, CD112 has been reported to be a receptor for herpesvirus entry into cells
- This monoclonal antibody has been reported to block cell adhesion and herpesvirus entry
- Applications Reported: This R2.477 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This R2.477 antibody has been pre-titrated and tested by flow cytometric analysis of human peripheral blood cells
- This can be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain
- This protein is one of the plasma membrane components of adherens junctions
- It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses
- Variations in this gene have been associated with differences in the severity of multiple sclerosis
- Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Compare Similar Items
Show Difference
Antigen: CD112 (Nectin-2)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q92692
Gene Symbols: NECTIN2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5819
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: R2.477
Conjugate: APC
Gene: NECTIN2
Gene Alias: AI325026; AI987993; CD112; herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; MPH; Murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin cell adhesion molecule 2; Nectin2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; poliovirus sensitivity; PRR2; Pvr; Pvrl2; PVRR2; Pvs
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD112 (Nectin-2)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q92692
Gene Symbols:
NECTIN2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5819
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
R2.477
Conjugate:
APC
Gene:
NECTIN2
Gene Alias:
AI325026; AI987993; CD112; herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; MPH; Murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin cell adhesion molecule 2; Nectin2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; poliovirus sensitivity; PRR2; Pvr; Pvrl2; PVRR2; Pvs
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD127
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P16872
Gene Symbols: Il7r
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16197
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBioSB/199 (SB/199)
Conjugate: APC
Gene: Il7r
Gene Alias: CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD127
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P16872
Gene Symbols:
Il7r
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16197
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBioSB/199 (SB/199)
Conjugate:
APC
Gene:
Il7r
Gene Alias:
CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD133 (Prominin-1)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: O43490
Gene Symbols: PROM1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8842
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: EMK08
Conjugate: APC
Gene: PROM1
Gene Alias: 4932416E19Rik; AC133; Antigen AC133; antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-1.s2; prominin-like 1; prominin-like protein 1; PROML1; RP41; STGD4
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD133 (Prominin-1)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O43490
Gene Symbols:
PROM1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8842
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
EMK08
Conjugate:
APC
Gene:
PROM1
Gene Alias:
4932416E19Rik; AC133; Antigen AC133; antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-1.s2; prominin-like 1; prominin-like protein 1; PROML1; RP41; STGD4
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD163
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q86VB7
Gene Symbols: CD163
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9332
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBioGHI/61 (GHI/61)
Conjugate: APC
Gene: CD163
Gene Alias: CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD163
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q86VB7
Gene Symbols:
CD163
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9332
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBioGHI/61 (GHI/61)
Conjugate:
APC
Gene:
CD163
Gene Alias:
CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ