50-112-3644
AIRE Monoclonal Antibody (TM-724), eFluor™ 570, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-112-3644-Each | In Stock | ₹ 24,782.45 |
50-112-3644 - Each
In Stock
Quantity
1
Base Price: ₹ 24,782.45
GST (18%): ₹ 4,460.841
Total Price: ₹ 29,243.291
Antigen
AIRE
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O43918
Gene Symbols
Aire
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
326
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone
TM-724
Conjugate
eFluor 570
Gene
Aire
Gene Alias
Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This TM-724 monoclonal antibody reacts with human Autoimmune Regulator (AIRE)
- This 58 kDa transcription factor is highly expressed within the perinuclear region of mature medullary thymic epithelial cells (mTECs)
- AIRE mRNA in the periphery has been observed in the lymph node, fetal liver, and intestines
- Furthermore, expression has been observed in dendritic cells, epithelial cells and PBMCs
- Studies demonstrate that AIRE is involved in thymocyte development, in particular the regulation of tissue-specific antigen expression during negative selection
- Other biological functions for AIRE include chemokine expression and antigen presentation
- As a result of alternative splicing, three isoforms have been reported
- The conditions autoimmune-polyendocrinopathy-candiasis-ectodermal-dystrophy (APECED) and autoimmune polyglandular syndrome type 1 (APS-1) arise from mutations in the human AIRE gene
- The TM-724 antibody is predicted to recognize all three isoforms of human AIRE (AIRE-1, AIRE-2, AIRE-3)
- Applications Reported: This TM-724 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, microscopy, immunohistochemical staining, and immunocytochemistry
- Applications Tested: This TM-724 antibody has been tested by immunohistochemistry on FFPE human thymus at less than or equal to 10 μg/mL using low pH antigen retrieval
- AIRE Monoclonal antibody specifically detects AIRE in Human samples
- It is validated for Immunocytochemistry, Immunohistochemistry (Paraffin).
Compare Similar Items
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Antigen: AIRE
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O43918
Gene Symbols: Aire
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 326
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: TM-724
Conjugate: eFluor 570
Gene: Aire
Gene Alias: Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
AIRE
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O43918
Gene Symbols:
Aire
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
326
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
TM-724
Conjugate:
eFluor 570
Gene:
Aire
Gene Alias:
Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Vinculin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P18206, P85972, Q64727
Gene Symbols: VCL
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22330, 305679, 7414
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 7F9
Conjugate: eFluor 570
Gene: VCL
Gene Alias: 9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Vinculin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P18206, P85972, Q64727
Gene Symbols:
VCL
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22330, 305679, 7414
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
7F9
Conjugate:
eFluor 570
Gene:
VCL
Gene Alias:
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Vimentin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P08670, P09654, P31000
Gene Symbols: Vim
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 420519, 477991, 7431, 81818
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: V9
Conjugate: eFluor 570
Gene: Vim
Gene Alias: cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species: Mouse
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Canine, Chicken, Human, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Vimentin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P08670, P09654, P31000
Gene Symbols:
Vim
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
420519, 477991, 7431, 81818
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
V9
Conjugate:
eFluor 570
Gene:
Vim
Gene Alias:
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species:
Mouse
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Canine, Chicken, Human, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: 0.2 mg/mL
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: Liquid
Applications: __
Clone: __
Conjugate: eFluor 615
Gene: __
Gene Alias: __
Host Species: __
Quantity: 25 μg
Primary or Secondary: __
Target Species: __
Product Type: Streptavidin Conjugate (fluorescent)
Isotype: __
Antigen:
__
Classification:
__
Concentration:
0.2 mg/mL
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
Liquid
Applications:
__
Clone:
__
Conjugate:
eFluor 615
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
25 μg
Primary or Secondary:
__
Target Species:
__
Product Type:
Streptavidin Conjugate (fluorescent)
Isotype:
__