50-112-4062

KLRG1 Monoclonal Antibody (2F1), APC-eFluor™ 780, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-112-4062-Each-of-1 In Stock ₹ 34,138.44

50-112-4062 - Each of 1

₹ 34,138.44

In Stock

Quantity

1

Base Price: ₹ 34,138.44

GST (18%): ₹ 6,144.919

Total Price: ₹ 40,283.359

Antigen

KLRG1

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O88713

Gene Symbols

Klrg1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

50928

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

2F1

Conjugate

APC-eFluor 780

Gene

Klrg1

Gene Alias

2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

Host Species

Syrian Hamster

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Description: This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA)
  • KLRG1 is a homodimer of glycosylated 30-38 kDa subunits and contains a cytoplasmic motif similar to the immunoreceptor tyrosine-based inhibitory motif (ITIM)
  • Rat MAFA was identified as an antigen specific to rat mast cells; however, the expression of mouse KLRG1/MAFA using 2F1 has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells
  • This antigen is expressed on approximately one-third of mouse NK cells and a subset of T cells
  • MHC class I molecules regulate KLRG1 via interactions with class I-specific inhibitory Ly49 molecules and SHP-1 signaling
  • Although KLRG1 and Ly49 are both lectin-like inhibitory receptors that are regulated by class I MHC expression, the effects of this on cell surface expression of these molecules are opposing, and the underlying regulatory mechanisms distinct
  • Applications Reported: This 2F1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 2F1 antibody has been tested by flow cytometric analysis of mouse spleen cells
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains
  • These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1
  • KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells
  • NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

Compare Similar Items

Show Difference

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Fischer Scientific

50-112-4062

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Antigen:
KLRG1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O88713

Gene Symbols:
Klrg1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50928

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2F1

Conjugate:
APC-eFluor 780

Gene:
Klrg1

Gene Alias:
2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

Host Species:
Syrian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Antigen:
FceR1 alpha

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
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Gene Symbols:
FCER1A

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14125

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MAR-1

Conjugate:
APC-eFluor 780

Gene:
FCER1A

Gene Alias:
alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3

Host Species:
Armenian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Antigen:
Ly-6G/Ly-6C

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

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Gene Symbols:
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Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100041546, 17067, 546644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
RB6-8C5

Conjugate:
APC-eFluor 780

Gene:
Ly6c2

Gene Alias:
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Host Species:
Rat

Quantity:
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Primary or Secondary:
Primary

Target Species:
Mouse

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Antigen:
IgD

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01881

Gene Symbols:
Ighd

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
380797

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
11-26c (11-26)

Conjugate:
APC-eFluor 780

Gene:
Ighd

Gene Alias:
IgD; Igh-5; IGHD; immunoglobulin heavy constant delta

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ