50-112-4452

IL-12 p35 Monoclonal Antibody (4D10p35), eFluor™ 660, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-112-4452-Each-of-1 In Stock ₹ 14,202.96

50-112-4452 - Each of 1

₹ 14,202.96

In Stock

Quantity

1

Base Price: ₹ 14,202.96

GST (18%): ₹ 2,556.533

Total Price: ₹ 16,759.493

Antigen

IL-12 p35

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P43431

Gene Symbols

IL12A

Immunogen

Mouse IL-35-Fc recombinant protein

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

4D10p35

Conjugate

eFluor 660

Gene

IL12A

Gene Alias

CLMF; CLMF p35; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; il 12; IL-12 subunit p35; IL-12, subunit p35; Il12a; IL-12A; IL12p35; IL-12p35; IL35 subunit; ILN; Interleukin; Interleukin 12; interleukin 12 p35 subunit; interleukin 12, p35; interleukin 12a; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); Interleukin12; interleukin-12 alpha chain; interleukin-12 beta p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NKSF1; P35

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16159

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Description

  • Description: This 4D10p35 monoclonal antibody reacts with mouse p35, a component of two of the four members of the interleukin (IL)-12 family of cytokines
  • The IL-12 family members are heterodimeric cytokines composed of an alpha-chain, such as p35, and a beta-chain, such as p40
  • The alpha-chain proteins are thought to be the limiting factors for secretion of IL-12 family member cytokines, as expression of the alpha-chain is more restricted than that of the beta-chain proteins, and the two subunits may need to be co-expressed in order for cytokine secretion to occur
  • IL-12 family members are secreted primarily by antigen-presenting cells in response to various TLR agonists and other inflammatory stimuli
  • The exact types of stimuli present and kinetics of stimulation determine the balance of IL-12 family member production
  • The p35 protein was first identified as part of the IL-12 cytokine, which is also known as IL-12p70
  • Secretion is induced by IFN gamma and agonists of TLR3, 4, or 7 and is inhibited by Th2 cytokines
  • IL-12 is essential for the differentiation and maintece of Th1 cells
  • The other subunit, p40, is expressed in much higher quantities than p35, and may be secreted independently as a monomer or homodimer
  • Free p40 may act as an antagonist of IL-12 function
  • More recently, p35 was also found to dimerize with EBI3 (Epstein-Barr Virus-Induced Gene 3) to form IL-35
  • Interleukin 12A is a novel signaling cytokine belonging to the Interleukin-6 protein superfamily
  • Interleukin-12 alpha chain precursor (IL-12A) is a 35-kD subunit of disulfide-linked heterodimer of cytokine IL-12 and has a broad array of biological activities
  • Reports suggest that IL-12A can act as a growth factor for activated T and NK cells and enhance the lytic activity of NK/lymphokine-activated Killer cells
  • IL-12A stimulates the production of IFN-gamma by resting PBMC as well as T-cell-independent induction of interferon (IFN)-gamma, and helps in the differentiation of both Th1 and Th2 cells
  • It is also involved in positive regulation of tyrosine phosphorylation of Stat4 protein
  • The signaling process of IL-12A in innate immunity requires nitric oxide synthase 2A
  • Along with EBI3, IL-12A forms a novel heterodimeric cytokine, designated as interleukin-35 (IL-35), that may be specifically produced by T reg cells and is required for maximal suppressive activity.

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Img

Fischer Scientific

50-112-4452

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Antigen:
IL-12 p35

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P43431

Gene Symbols:
IL12A

Immunogen:
Mouse IL-35-Fc recombinant protein

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
4D10p35

Conjugate:
eFluor 660

Gene:
IL12A

Gene Alias:
CLMF; CLMF p35; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; il 12; IL-12 subunit p35; IL-12, subunit p35; Il12a; IL-12A; IL12p35; IL-12p35; IL35 subunit; ILN; Interleukin; Interleukin 12; interleukin 12 p35 subunit; interleukin 12, p35; interleukin 12a; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); Interleukin12; interleukin-12 alpha chain; interleukin-12 beta p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NKSF1; P35

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16159

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-112-4467

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Antigen:
IL-9

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P15247

Gene Symbols:
Il9

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
RM9A4

Conjugate:
eFluor 660

Gene:
Il9

Gene Alias:
cytokine P40; homolog of mouse T cell and mast cell growth factor 40; HP40; IL9; IL-9; ILN; Interleukin; interleukin 9; Interleukin9; interleukin-9; P40; p40 cytokine; p40 T-cell and mast cell growth factor; T-cell growth factor P40

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16198

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

50-112-4470

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Antigen:
SSEA1

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P22083, Q11127

Gene Symbols:
FUT4

Immunogen:
__

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry

Clone:
eBioMC-480 (MC-480)

Conjugate:
eFluor 660

Gene:
FUT4

Gene Alias:
FUTIV, Lewis X, SSEA-1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14345, 2526

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-112-4477

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Antigen:
Pan Cytokeratin

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P02533, P02535, P02538, P04104, P04264, P05783, P05784, P05787, P07744, P08727, P08729, P08730, P08779, P11679, P12035, P13645, P13646, P13647, P19001, P19012, P19013, P35908, P50446, Q01546, Q04695, Q29426, Q3TTY5, Q3UV17, Q61414, Q61781, Q6EIY9, Q6EIZ0, Q6EIZ1, Q6IFZ6, Q7Z794, Q922U2, Q9DCV7, Q9QWL7, Q9Z2K1

Gene Symbols:
KRT1, KRT10, KRT13, KRT14, KRT15, KRT16, KRT17, KRT18, KRT19, KRT2, KRT3, KRT4, KRT5, Krt6a, KRT7, KRT76, KRT77, KRT8

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rabbit, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
AE1/AE3

Conjugate:
eFluor 660

Gene:
KRT2

Gene Alias:
2310016L08Rik; 3300001P10Rik; 39.1; 40-kDa keratin intermediate filament; 47 kDa cytokeratin; 56 kDa cytokeratin; 57kd keratin; 57kDa keratin; 58 kDa cytokeratin; 60-kDa keratin; 63kDa Keratin; 65 kDa cytokeratin; 67 kDa cytokeratin; AA960620; adult keratin; AI324768; AI528832; AI626930; AI663979; AL022697; alpha keratin; AU019895; AW108092; AW146334; basic epidermal type II cytokeratin (carboxy-terminal region, clone pUF164); BB005427; BCIE; BIE; Card2; cell proliferation-inducing gene 46 protein; CK 2e; CK1; CK-1; CK10; CK-10; CK13; CK-13; CK14; CK-14; CK15; CK-15; CK16; CK-16; CK-17; CK18; CK-18; CK19; CK-19; CK-1B; CK-2e; CK3; CK-3; CK4; CK-4; CK5; CK-5; ck55; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; CK7; CK-7; CK8; CK-8; CYK18; CYK4; CYK8; CYKER; cytokeratin 1; cytokeratin 10; cytokeratin 13; cytokeratin 14; cytokeratin 15; cytokeratin 16; cytokeratin 18; cytokeratin 19; cytokeratin 3; cytokeratin 4; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin 7; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin endo B; cytokeratin otokeratin; cytokeratin type II; cytokeratin type II, component Ib/c; cytokeratin type II, component III; cytokeratin VIB; cytokeratin VII; cytokeratin-1; Cytokeratin-10; cytokeratin-13; Cytokeratin-14; cytokeratin-15; Cytokeratin-16; cytokeratin-17; Cytokeratin-18; cytokeratin-19; Cytokeratin-1B; Cytokeratin-2e; cytokeratin-3; Cytokeratin-4; cytokeratin-5; Cytokeratin-6A; cytokeratin-6B; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; cytokeratin-7; Cytokeratin-8; cytokeratin-A; Cytoskeletal 57 kDa keratin; D130054E02Rik; D15Wsu77e; DDD; DDD1; ear specific cytokeratin; EBS2; ebs3; ebs4; EGK_03684; EGK_03685; EHK; EHK1; Endo B; EndoA; EndoC; epidermal keratin 10; epidermal keratin VII; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; epidermolysis bullosa simplex, Dowling-Meara, Koebner; epidermolytic hyperkeratosis 1; epidermolytic hyperkeratosis; keratosis palmaris et plantaris; epithelial keratin 1; epithelial keratin 10; epithelial keratin 2e; Epithelial keratin-1; Epithelial keratin-2e; EPPK; fgk; fin and gill keratin; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; GK-19; Hair alpha protein; HMWCK; Hom s 5; I79_019823; I79_021074; I79_023185; I79_024335; intermediate filament protein; K1; K10; K13; K14; K15; K16; K17; K18; K19; K1B; K1C1; K1CO; K1CP; K1CS; K2C7; K2C8; K2e; K3; K3 keratin; K4; K5; K6A; K6a keratin; K6C; K6D; K7; K77; K8; Ka10; Ka13; Ka14; Ka15; Ka16; Ka17; Ka19; kamp-keratin derived antimicrobial peptide; Kb1; Kb2; Kb4; Kb7; KDAMP; KER1; Ker10; Ker2; KERA; keratin; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 10; keratin 10 (epidermolytic hyperkeratosis); keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); keratin 10, type I; keratin 10, type I L homeolog; keratin 10, type I S homeolog; keratin 12, gene 2 S homeolog; keratin 13; keratin 13, type I; keratin 13, type I S homeolog; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 14, type I L homeolog; keratin 15; keratin 15, gene 1 S homeolog; keratin 15, type I; keratin 16; keratin 16 (focal non-epidermolytic palmoplantar keratoderma); keratin 16, type I; keratin 16, type I S homeolog; keratin 17; keratin 17 L homeolog; keratin 17, type I; keratin 17, type I L homeolog; keratin 18; keratin 18, type I; keratin 19; keratin 19 S homeolog; keratin 19 S homeolog; keratin 19; keratin 19, type I; Keratin 1B; keratin 2; keratin 2 (epidermal ichthyosis bullosa of Siemens); keratin 2 epidermis; keratin 2, type II; keratin 24; keratin 2A; keratin 2A (epidermal ichthyosis bullosa of Siemens); keratin 3; keratin 3, type II; keratin 4; keratin 4, type II; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types)

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100009029, 100341120, 100341376, 100344183, 100344942, 100345579, 100348388, 100348891, 100352658, 100353162, 100353415, 100353668, 100354174, 100424400, 100425096, 100426180, 100426330, 100682832, 100683333, 100683401, 100685323, 100685404, 100685481, 100687760, 103348273, 106994041, 110308, 110310, 16661, 16663, 16664, 16665, 16666, 16667, 16668, 16669, 16678, 16681, 16682, 16687, 16691, 374454, 3848, 3849, 3850, 3851, 3852, 3853, 3855, 3856, 3858, 3860, 3861, 3866, 3868, 3872, 3875, 3880, 406220, 444850, 444857, 477601, 477602, 486513, 486518, 486523, 490977, 490978, 490983, 491006, 51350, 697425, 699194, 699320, 699567, 700060, 700449, 702153, 705390, 706830, 707236, 718983, 77055

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid